Results 61 to 70 of about 7,550 (263)
Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons
Advanced Science, EarlyView.Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu +12 morewiley +1 more sourcePolydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement
Advanced Science, EarlyView.Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang +10 morewiley +1 more sourceSpatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy
Advanced Science, EarlyView.We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu +9 morewiley +1 more sourceEuclid Quick Data Release (Q1)
Astronomy & AstrophysicsThis paper describes the VIS processing function (VIS PF) of the Euclid ground segment pipeline, which processes and calibrates raw data from the VIS camera.McCracken H. J., Benson K., Dolding C., Flanet T., Grenet C., Herent O., Hudelot P., Laigle C., Leroy G., Liebing P., Massey R., Mottet S., Nakajima R., Nguyen-Kim H. N., Nightingale J. W., Skottfelt J., Smith L. C., Soldano F., Vilenius E., Wander M., von Wietersheim-Kramsta M., Akhlaghi M., Aussel H., Awan S., Azzollini R., Basset A., Candini G. P., Casenove P., Cropper M., Hoekstra H., Israel H., Khalil A., Kuijken K., Mellier Y., Miller L., Niemi S.-M., Page M. J., Paterson K., Schirmer M., Walton N. A., Zacchei A., Barrios J. P. L. G., Erben T., Hayes R., Kegerreis J. A., Lagattuta D. J., Lançon A., Aghanim N., Altieri B., Amara A., Andreon S., Appleton P. N., Auricchio N., Baccigalupi C., Baldi M., Balestra A., Bardelli S., Battaglia P., Belikov A. N., Bender R., Bernardeau F., Biviano A., Bonchi A., Branchini E., Brescia M., Brinchmann J., Camera S., Cañas-Herrera G., Capobianco V., Carbone C., Carretero J., Casas S., Castander F. J., Castellano M., Castignani G., Cavuoti S., Chambers K. C., Cimatti A., Colodro-Conde C., Congedo G., Conselice C. J., Conversi L., Copin Y., Courbin F., Courtois H. M., Da Silva A., da Silva R., Degaudenzi H., De Lucia G., Di Giorgio A. M., Dinis J., Dole H., Dubath F., Dupac X., Dusini S., Ealet A., Escoffier S., Fabricius M., Farina M., Farinelli R., Ferriol S., Finelli F., Fosalba P., Fotopoulou S., Fourmanoit N., Frailis M., Franceschi E., Galeotta S., George K., Gillard W., Gillis B., Giocoli C., Gómez-Alvarez P., Gracia-Carpio J., Granett B. R., Grazian A., Grupp F., Guzzo L., Hailey M., Haugan S. V. H., Hoar J., Holmes W., Hormuth F., Hornstrup A., Jahnke K., Jhabvala M., Joachimi B., Keihänen E., Kermiche S., Kiessling A., Kilbinger M., Kubik B., Kümmel M., Kunz M., Kurki-Suonio H., Le Boulc’h Q., Le Brun A. M. C., Le Mignant D., Ligori S., Lilje P. B., Lindholm V., Lloro I., Mainetti G., Maino D., Maiorano E., Mansutti O., Marcin S., Marggraf O., Martinelli M., Martinet N., Marulli F., Masters D. C., Maurogordato S., Medinaceli E., Mei S., Melchior M., Meneghetti M., Merlin E., Meylan G., Mora A., Moresco M., Moscardini L., Neissner C., Nichol R. C., Padilla C., Paltani S., Pasian F., Pedersen K., Percival W. J., Pettorino V., Pires S., Polenta G., Poncet M., Popa L. A., Pozzetti L., Racca G. D., Raison F., Rebolo R., Renzi A., Rhodes J., Riccio G., Romelli E., Roncarelli M., Rossetti E., Rusholme B., Saglia R., Sakr Z., Sánchez A. G., Sapone D., Sartoris B., Schewtschenko J. A., Schneider P., Schrabback T., Secroun A., Seidel G., Seiffert M., Serrano S., Simon P., Sirignano C., Sirri G., Spurio Mancini A., Stanco L., Steinwagner J., Tallada-Crespí P., Tavagnacco D., Taylor A. N., Teplitz H. I., Tereno I., Tessore N., Toft S., Toledo-Moreo R., Torradeflot F., Tutusaus I., Valentijn E. A., Valenziano L., Valiviita J., Vassallo T., Verdoes Kleijn G., Veropalumbo A., Wang Y., Weller J., Zamorani G., Zerbi F. M., Zinchenko I. A., Zucca E., Allevato V., Ballardini M., Bolzonella M., Bozzo E., Burigana C., Cabanac R., Calabrese M., Cappi A., Di Ferdinando D., Escartin Vigo J. A., Fabbian G., Gabarra L., Huertas-Company M., Martín-Fleitas J., Matthew S., Mauri N., Metcalf R. B., Pezzotta A., Pöntinen M., Porciani C., Risso I., Scottez V., Sereno M., Tenti M., Viel M., Wiesmann M., Akrami Y., Andika I. T., Anselmi S., Archidiacono M., Atrio-Barandela F., Benoist C., Bergamini P., Bertacca D., Bethermin M., Bisigello L., Blanchard A., Blot L., Borgani S., Borlaff A. S., Brown M. L., Bruton S., Calabro A., Camacho Quevedo B., Caro F., Carvalho C. S., Castro T., Cogato F., Conseil S., Cooray A. R., Cucciati O., Davini S., De Paolis F., Desprez G., Díaz-Sánchez A., Diaz J. J., Di Domizio S., Diego J. M., Duc P.-A., Enia A., Fang Y., Ferguson A. M. N., Ferrari A. G., Finoguenov A., Fontana A., Franco A., Ganga K., García-Bellido J., Gasparetto T., Gautard V., Gaztanaga E., Giacomini F., Gianotti F., Gonzalez A. H., Gozaliasl G., Gregorio A., Guidi M., Gutierrez C. M., Hall A., Hartley W. G., Hernández-Monteagudo C., Hildebrandt H., Hjorth J., Kajava J. J. E., Kang Y., Kansal V., Karagiannis D., Kiiveri K., Kirkpatrick C. C., Kruk S., Le Graet J., Legrand L., Lembo M., Lepori F., Lesci G. F., Lesgourgues J., Leuzzi L., Liaudat T. I., Liu S. J., Loureiro A., Macias-Perez J., Maggio G., Magliocchetti M., Mannucci F., Maoli R., Martins C. J. A. P., Maurin L., McPartland C. J. R., Miluzio M., Monaco P., Montoro A., Moretti C., Morgante G., Murray C., Nadathur S., Naidoo K., Navarro-Alsina A., Nesseris S., Passalacqua F., Patrizii L., Pisani A., Potter D., Quai S., Radovich M., Reimberg P., Rocci P.-F., Rodighiero G., Rollins R. P., Sacquegna S., Sahlén M., Sanders D. B., Sarpa E., Scarlata C., Schneider A., Schultheis M., Sciotti D., Sellentin E., Shankar F., Silvestri A., Tanidis K., Tao C., Testera G., Tewes M., Teyssier R., Tosi S., Troja A., Tucci M., Valieri C., Venhola A., Vergani D., Verza G., Vielzeuf P., Weaver J. R., Scott D. +378 moredoaj +1 more sourceFour-Mirror Plane Objectives with Intermediate Image
Наука и техника, 2005 The paper considers lenses with an intermediate image consisting of four mirrors. Two mirrors can be united in a mono-block (double mirror) and have central apertures for light beam passing. Calculation of design factors is given and the problem of image N. K. Artiuokhinadoaj +1 more sourceTargeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety
Advanced Science, EarlyView.Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...Meng‐Ge Li, Xiao‐Bo Qian, Hai‐Long Zhang, Di Li, Ling Ji, Xin‐Chun Xu, Jia‐Sheng Ding, Li‐Jun Yin, Li Zhang, Guang‐Yin Xu, Rong Gao +10 morewiley +1 more source
