Results 101 to 110 of about 1,208,754 (253)

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Covalent Organic Framework Colloids With Core‐Shell Donor/Acceptor Architecture and Ultralong‐Lived Charge‐Separated States

Angewandte Chemie, EarlyView.
Uniform core‐shell colloidal particles of Covalent Organic Frameworks (COFs) are synthesized by a seeded growth of electron‐acceptor COF shells on electron‐donor COF cores. The resulting p‐n heterojunction enables efficient separation of photogenerated charges, which persist for minutes. These core‐shell COFs show efficient CO2 photoreduction to CO and
Ting Yu, Cory Ruchlin, Tong Li, Mohammad Hossein Gohari, Zhechang He, Zeina Chamseddine, Chang Wan Kang, Dongling Ma, Dmytro F. Perepichka   +8 more
wiley   +2 more sources

A cone-beam photon-counting CT dataset for spectral image reconstruction and deep learning

Scientific Data
Photon-counting CT has gained significant attention in recent years; however, publicly available datasets for spectral reconstruction and deep learning training remain limited.
Enze Zhou, Wenjian Li, Wenting Xu, Kefei Wan, Yuwei Lu, Shangbin Chen, Gang Zheng, Tianwu Xie, Qian Liu   +8 more
doaj   +1 more source

Immunomagnetic‐MXene Bifunctional Probes for Ultrasensitive and Specific Terahertz Metasensing of Tumor‐Derived Exosomes

Advanced Science, EarlyView.
An immunomagnetic‐MXene bifunctional probe integrated with THz metamaterials enables ultrasensitive and specific detection of pancreatic cancer‐derived exosomes. Dual biomarker recognition ensures high specificity, while MXene signal amplification achieves a detection limit of 647 particles mL−1.
Weidong Jin, Jiyue Chen, Fengxin Xie, Huiyan Tian, Xuechen Dou, Yanqi Han, Lu Zhang, Jining Li, Xiang Yang   +8 more
wiley   +1 more source

TADF‐Active Tetrazole Luminophores for Visible‐Light Functionalization of Nanoparticles and Surfaces

Angewandte Chemie, EarlyView.
A series of tetrazoles are reported that undergo 1,3‐dipolar cycloadditions with alkene and alkyne substrates, generating (dihydro)pyrazole products that exhibit thermally activated delayed fluorescence (TADF). The “photo‐click” reactivity of these tetrazoles is leveraged to functionalize nanoparticles and surfaces with TADF‐active chromophores ...
Ryoga Hojo, Katrina Bergmann, Siyuan L. Xie, Connor S. Durfy, William L. Primrose, Athan T. Gogoulis, Seja A. Elgadi, Mitchell J. Demchuk, Thomas Kalab, Peiqi Hu, Eva M. Nichols, Zachary M. Hudson   +11 more
wiley   +2 more sources

Decoupling Chemical and Mechanical Contributions to Capacity Fading in Ni‐Rich Cathodes for Sulfide‐Based All‐Solid‐State Batteries

Advanced Energy Materials, EarlyView.
Ni‐rich cathodes in sulfide‐based ASSBs undergo intertwined (electro)chemical and mechanical degradation. Here, a new diagnostic framework is presented to decouple each contribution by partitioning capacity fading into charge and discharge fading.
Jangwhan Seok, Chanyou Chung, Hyunbeom Lee, Subin Ahn, Seongeun Lee, Sangbin Park, Sunhyun Hwang, Jaeyoung Kim, Jeonghyun Seo, Sungwoo Noh, Juyeong Seong, Sangheon Lee, Won‐Sub Yoon   +12 more
wiley   +1 more source

Ultra-high spatial resolution at photon-counting computed tomography: technical insights and sustainable applications in cardiothoracic imaging

European Radiology Experimental
The latest technological advancements in CT enable the exploration of unprecedented limits of spatial resolution in in vivo imaging. Nowadays, ultra-high-resolution imaging is available by using CT with detector elements at or smaller than 0.25 mm along ...
Mariaelena Occhipinti, Alberto Clemente, Carmelo De Gori, Vincenzo Positano, Danilo Neglia, Simona Celi, Antonella Meloni, Sergio Berti, Filippo Cademartiri   +8 more
doaj   +1 more source

Advancing Aortic Dissection Imaging: First Clinical Experience of Photon-Counting CT with Ultra-Fast Spectral Imaging

Diagnostics
Background: Computed tomography (CT) is the standard of reference for diagnosis and follow-up in aortic dissection (AD). Localizing the entry and identifying false and true lumen are as important as differing post-treatment changes from contrast media ...
Daniel Dillinger, Maria Weiss, Hanns L. Kaatsch, Christian Bauer, Achim Hagen, Matthias F. Froelich, Stephan Waldeck, Daniel Overhoff   +7 more
doaj   +1 more source

Experimentally Determined Spatiotemporal Charge Carrier Dynamics for the Development of Particulate Photocatalysts

Advanced Energy Materials, EarlyView.
This review looks at the different experimental techniques that measure spatiotemporal charge carrier dynamics. This information is viewed in the context of particulate photocatalysts, outlining the insights these techniques provide and how they advance our understanding.
Sutripto Khasnabis, Robert Godin
wiley   +1 more source

Atherosclerotic plaque features relevant to rupture-risk detected by clinical photon-counting CT ex vivo: a proof-of-concept study

European Radiology Experimental
Background To identify subjects with rupture-prone atherosclerotic plaques before thrombotic events occur is an unmet clinical need. Thus, this proof-of-concept study aims to determine which rupture-prone plaque features can be detected using clinically ...
Annelie Shami, Jiangming Sun, Chrysostomi Gialeli, Hanna Markstad, Andreas Edsfeldt, Marie-Louise Aurumskjöld, Isabel Gonçalves   +6 more
doaj   +1 more source