Results 241 to 250 of about 568,064 (303)

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Virtual photon-counting micro-CT platform for simulation of head and neck cancer imaging in mice. [PDF]

Phys Med Biol
Nadkarni R, Clark DP, Allphin AJ, Qi Y, Mowery YM, Segars WP, Badea CT.   +6 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Ultra-low contrast agent dosage in photon-counting CT angiography of the thoracoabdominal aorta. [PDF]

Eur J Radiol Open
Hennes JL, Krompaß K, Huflage H, Pannenbecker P, Dazeh RS, Grunz JP, Hartung V, Bley TA, Gruschwitz P.   +8 more
europepmc   +1 more source

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

A Practical Rule-of-Thumb to Adapt Contrast Media Dose in Photon-counting Detector CT: The 10-to-5 Rule. [PDF]

Invest Radiol
Jeukens CRLPN, Martens B, Vandewall J, Jasper S, Schrijnemaekers G, Wildberger JE, Flohr TG.   +6 more
europepmc   +1 more source

It Is All About Energy-the Changing Role of X-ray Photons in Photon-counting Detector Computed Tomography: What the Radiologist Needs to Know About kV and keV. [PDF]

Invest Radiol
Hoeijmakers EJI, Martens B, Wildberger JE, Flohr TG, Jeukens CRLPN.   +4 more
europepmc   +1 more source

Photon-counting detector computing tomography in treatment planning of head-and-neck cancer. [PDF]

Phys Imaging Radiat Oncol
Lamaj E, Wohlfahrt P, Wilke L, Alkadhi H, Bertini N, Gabrys H, Guckenberger M, Balermpas P, Tanadini-Lang S, Psoroulas S.   +9 more
europepmc   +1 more source

Characterization of a photon counting micro computed tomography laboratory setup. [PDF]

Radiat Prot Dosimetry
Celander M, Krüger R, Peruzzi N, Aurumskjöld ML, Bech M.   +4 more
europepmc   +1 more source