Results 251 to 260 of about 54,778 (306)

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Multi-parameter fluorescence lifetime imaging for high-noise neuroscience applications. [PDF]

Biomed Opt Express
Salem AM, Lacny CM, Ivey PE, Qi W, Rochet JC, Webb KJ.   +5 more
europepmc   +1 more source

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

Advanced Science, EarlyView.
Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go, Dahee Lee, Minji Kim, Kiseok Han, Gyuho Choi, ChanHui Song, Sanghyun Ahn, Yerim Lee, Jinyoung Lee, Yingxiao Wang, Jung‐Soo Suh, Hwayoung Yun, Tae‐Jin Kim   +12 more
wiley   +1 more source

Nickel Doping Unlocks Ambient-Condition Photostability in Individual Cesium Lead Bromide Perovskite Quantum Dots. [PDF]

Nano Lett
Ryu J, Krivenkov V, Olejniczak A, Arruabarrena M, Janovec J, Hadjadj SE, Ilyn M, Leonardo A, Martínez-Martínez V, Ayuela A, Nikitin AY, Rakovich Y.   +11 more
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Input to the European strategy for particle physics: strong-field quantum electrodynamics. [PDF]

Eur Phys J Plus
Sarri G, King B, Blackburn T, Ilderton A, Boogert S, Bulanov SS, Bulanov SV, Di Piazza A, Ji L, Karbstein F, Keitel CH, Krajewska K, Malka V, Mangles SPD, Mathieu F, McKenna P, Meuren S, Mirzaie M, Ridgers C, Seipt D, Thomas AGR, Uggerhøj U, Vranic M, Wing M.   +23 more
europepmc   +1 more source

Dosimetric comparison of scanned proton therapy and volumetric modulated arc therapy in isodose-prescribed stereotactic body radiotherapy for lung cancer. [PDF]

J Radiat Res
Tominaga Y, Endo H, Kato T, Wakisaka Y, Higashikawa T, Murakami M, Yamamoto M.   +6 more
europepmc   +1 more source

Towards accurate penetration depth estimation in near-infrared spectroscopy: a quantitative analysis of source-detector distance dependence in porcine kidney models. [PDF]

Biomed Opt Express
Khurana AS, Khodavandi A, Amani Tehrani I, Shadgan B.   +3 more
europepmc   +1 more source

Photon statistics in attenuators

, 2018
openaire   +2 more sources

Quantum light drives electrons strongly at metal needle tips. [PDF]

Nat Phys
Heimerl J, Rasputnyi A, Pölloth J, Meier S, Chekhova M, Hommelhoff P.   +5 more
europepmc   +1 more source