Results 51 to 60 of about 267,241 (294)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Coupled Photon and Heat Transport Simulation inside Biological Tissue for Laser Therapy

Journal of Thermal Science and Technology, 2009
The objective of this study is to develop a new simulator for laser therapy. In order to minimize undesired effects on the laser therapy, it is important to precisely predict for heat and photon transport inside a biological tissue. In the present study,
Atsushi SAKURAI, Isami NITTA, Shigenao MARUYAMA, Junnosuke OKAJIMA, Koji MATSUBARA   +4 more
doaj   +1 more source

Transport of pseudothermal photons through an anharmonic cavity

Scientific Reports, 2021
Under nonequilibrium conditions, quantum optical systems reveal unusual properties that might be distinct from those in condensed matter. The fundamental reason is that photonic eigenstates can have arbitrary occupation numbers, whereas in electronic ...
Dmitriy S. Shapiro
doaj   +1 more source

Non-reciprocal few-photon devices based on chiral waveguide-emitter couplings

, 2016
We demonstrate the possibility of designing efficient, non reciprocal few-photon devices by exploiting the chiral coupling between two waveguide modes and a single quantum emitter. We show how this system can induce non-reciprocal photon transport at the
Garcia-Vidal, F. J., Gonzalez-Ballestero, C., Gonzalez-Tudela, A., Moreno, Esteban   +3 more
core   +1 more source

Simulation studies of photon-assisted quantum transport [PDF]

Physical Review B, 1996
Direct numerical simulations were performed to investigate conditions for the strong effects of photonassisted quantum transport. Transmission probabilities of incident electrons as Gaussian wave packets were calculated for single- and double-barrier structures irradiated by electromagnetic fields that were focused within a finite region j ac .
, Yakubo, , Feng, , Hu
openaire   +3 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Modelling atomic relaxation and bremsstrahlung in the deterministic code STREAM

Nuclear Engineering and Technology
STREAM, developed by the Computational Reactor Physics and Experiment laboratory (CORE) of the Ulsan National Institute of Science and Technology (UNIST), is a deterministic neutron- and photon-transport code primarily designed for light water reactor ...
Nhan Nguyen Trong Mai, Kyeongwon Kim, Deokjung Lee   +2 more
doaj   +1 more source

Harmonic radiation contribution and X-ray transmission at the Small Quantum Systems instrument of European XFEL

Journal of Synchrotron Radiation, 2023
Transmission measurements of the soft X-ray beamline to the Small Quantum Systems (SQS) scientific instrument at the SASE3 undulator of European XFEL are presented.
Thomas M. Baumann, Rebecca Boll, Alberto De Fanis, Patrik Grychtol, Markus Ilchen, Ulf Fini Jastrow, Masahiro Kato, Christoph Lechner, Theophilos Maltezopoulos, Tommaso Mazza, Jacobo Montaño, Valerija Music, Yevheniy Ovcharenko, Nils Rennhack, Daniel E. Rivas, Norio Saito, Philipp Schmidt, Svitozar Serkez, Andrey Sorokin, Sergey Usenko, Jiawei Yan, Gianluca Geloni, Takahiro Tanaka, Kai Tiedtke, Michael Meyer   +24 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Transport theory and systems theory [PDF]

Nuclear Technology and Radiation Protection, 2005
The simulation of singular nonlinear transport equation is obtained via corresponding neutron or photon kinetic equation. The conditions for convergence of the non stationary transport process to ward the pure dif fusion across the equilibriums are ...
Rastović Danilo
doaj   +1 more source