Results 211 to 220 of about 18,161 (307)

Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles

Chemistry – A European Journal, EarlyView.
A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook, Blandine McKay, Craig Jamieson, Lee J. Edwards, Charlotte Harriman, Zackary S. Read, Simon T. Bate   +6 more
wiley   +1 more source

Chemiexcitation in Ex Vivo Porcine Skin Model. [PDF]

Pigment Cell Melanoma Res
Pospíšil P, Paculová V, Prasad A, Berecka M.   +3 more
europepmc   +1 more source

Photoinduced Hydrogenative Dearomatization With Homocoupling of Quinolines to Construct Octahydro‐4,4'‐biquinolines

Chemistry – A European Journal, EarlyView.
Dearomative homocoupling of quinolines into 1,1',2,2',3,3',4,4'‐octahydro‐4,4'‐biquinoline (OHBQ) is reported. The photoexcited boron complex, in situ generated from quinoline, HB(pin), and KOtBu, enables the unprecedented homocoupling of tetrahydroquinolines that is challenging in the ground state, expanding the chemical diversity of OHBQ derivatives.
Mone Suzuki, Asuha Shimose, Yuki Nagashima   +2 more
wiley   +1 more source

Efficacy of photodynamic therapy using 5-aminolevulinic acid-induced photosensitization is enhanced in pancreatic cancer cells with acquired drug resistance. [PDF]

Photodiagnosis Photodyn Ther
Liu Y, Mensah SK, Farias S, Khan S, Hasan T, Celli JP.   +5 more
europepmc   +1 more source

When Light Challenges Heat: Mechanistic Insights Into a Reaction Competing With Cadogan Cyclisation in Nitro‐Perylenediimides

Chemistry – A European Journal, EarlyView.
Visible‐light irradiation of nitro‐perylenediimide in the presence of triphenylphosphine reveals an unexpected pathway competing with the classical Cadogan cyclization. Mechanistic investigations uncover the rapid and selective formation of bay‐functionalized 1‐iminophosphorane‐12‐hydroxy perylenediimide derivatives.
Manuel Pedrón Laserna, Ilaria Ciofini, Piétrick Hudhomme   +2 more
wiley   +1 more source

Chemical and photoinduced interstrand crosslinking of oligo DNA duplexes containing 2'-deoxythioguanosines. [PDF]

Commun Chem
Osman JA, Onizuka K, Yamano Y, Nagatsugi F.   +3 more
europepmc   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

Chemistry – A European Journal, EarlyView.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi, Emily R. McGowan, Katherine A. Morgan, Jonathan M. White, Trevor A. Smith, Stacey E. Rudd, Paul S. Donnelly   +6 more
wiley   +1 more source

Bimetallic Au-Ag Nanoclusters as a Photo-Responsive Oxidase-Like Nanozyme for Antioxidant Detection and Intracellular Redox Analysis. [PDF]

Small Sci
Swain S, Chou IH, Mallick BC, Liu SC, Chen GS, Lin HY, Huang CH.   +6 more
europepmc   +1 more source

Phosphorescence of Heavy, T‐Shaped Pnictogen Trisamides in Solution at Room Temperature in the Near‐Infrared II Region

Chemistry – A European Journal, EarlyView.
The unique photophysical properties of heavy T‐shaped Sb and Bi trisamides are reported. A ligand‐to‐pnictogen charge‐transfer excitation from a redox‐active NNN pincer to a vacant pnictogen p‐orbital populates a triplet state that emits in the highly desirable NIR‐II region, with lifetimes up to the µs range.
Katharina L. Deuter, Sotirios Pavlidis, Rainer F. Winter, Peter Coburger, Josh Abbenseth   +4 more
wiley   +1 more source