Results 41 to 50 of about 44,938 (292)

Photosensitizer-Loaded Multifunctional Chitosan Nanoparticles for Simultaneous in Situ Imaging, Highly Efficient Bacterial Biofilm Eradication, and Tumor Ablation

, 2018
In recent decades, bacterial and viral infections and chronic inflammatory response have emerged as important causes of cancer. Also, infections remain a significant cause of morbidity and mortality in cancer patients.
Wenya Jiang, Hao Chen, Wenya Jiang (6167504), Jian Ji (830349), Kanghui Du, Hangdong Dai, Wei Chen (23863), Hangdong Dai (6167516), Hengrui Zhang, Jian Ji, Bailiang Wang, Bailiang Wang (2040325), Yishun Guo, Yingying Jin, Kanghui Du (6167513), Hao Chen (5190), Wei Chen, Lin Sun, Yishun Guo (6167510), Hengrui Zhang (6167507), Lin Sun (105539), Yingying Jin (3858145)   +21 more
core   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source

Nanomaterials as carriers to improve the photodynamic antibacterial therapy

Frontiers in Chemistry, 2022
The main treatment for bacterial infections is antibiotic therapy, but the emergence of bacterial resistance has severely limited the efficacy of antibiotics.
Houhe Liu, Yuan Jiang, Zhen Wang, Linping Zhao, Qianqian Yin, Min Liu   +5 more
doaj   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Photosensitizer in lipid nanoparticle: a nano-scaled approach to antibacterial function

Scientific Reports, 2017
Photosensitization-based antimicrobial therapy (PAT) is an alternative therapy aimed at achieving bacterial inactivation. Researchers use various photosensitizers to achieve bacterial inactivation.
Bishakh Rout, Chi-Hsien Liu, Wei-Chi Wu
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

In vitro reduction of pathogenic sporothrix schenckii fungus by photodynamic therapy

O Mundo da Saúde, 2017
Sporotrichosis is a disease that affects the lymph vessels, skin and some internal organs. Most cases are presented as a subacute chronic mycosis caused by the Sporothrix schenckii fungus; fairly common in tropical regions. The aim of this study was to
Gunther Monteiro de Paula Guirado, Ricardo Scarparo Navarro, Rodnei Dennis Rossoni, Juliana Campos Junqueira, Luciano dos Santos Feitosa   +4 more
doaj  

Co-Assembly of Graphene Oxide and Albumin/Photosensitizer Nanohybrids towards Enhanced Photodynamic Therapy

, 2016
The inactivation of photosensitizers before they reach the targeted tissues can be an important factor, which limits the efficacy of photodynamic therapy (PDT).
Yan, Xuehai, Kai Ma, Ma, Kai, Ma, Guanghui, Guanghui Ma, Xuehai Yan, Ruirui Xing, Qianli Zou, Liu, Yamei, Yamei Liu, Zou, Qianli, Tifeng Jiao, Xing, Ruirui, Jiao, Tifeng   +13 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Review of selective accumudation of photosensitizers with different chemical structure in tumor tissue

Biomedical Photonics, 2013
The review of available theories explaining mechanisms of photosensitizer selective accumulation in tumor tissue is represented in the article. Variants associated with both targeted delivery of compounds with different chemical structure to tumor and ...
E. A. Machinskaya, V. I. Ivanova-Radkevich   +1 more
doaj   +2 more sources