Results 161 to 170 of about 13,262 (302)

Design Principles for Next Generation of Small Organic Molecules for Photodynamics Therapy Revealed by Nonadiabatic Molecular Dynamics

open access: yesChemistry – A European Journal, EarlyView.
Molecular design reshapes the landscape of excited‐state relaxation. Nonadiabatic dynamics reveal how electronic structure guides population flow between competing pathways beyond static energetic arguments. ABSTRACT Nitrobenzochalcogenadiazole derivatives are emerging candidates for photodynamic therapy (PDT), yet the precise mechanisms governing ...
Vinícius N. da Rocha   +2 more
wiley   +1 more source

Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles

open access: yesChemistry – A European Journal, EarlyView.
A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook   +6 more
wiley   +1 more source

Photoinduced Hydrogenative Dearomatization With Homocoupling of Quinolines to Construct Octahydro‐4,4'‐biquinolines

open access: yesChemistry – A European Journal, EarlyView.
Dearomative homocoupling of quinolines into 1,1',2,2',3,3',4,4'‐octahydro‐4,4'‐biquinoline (OHBQ) is reported. The photoexcited boron complex, in situ generated from quinoline, HB(pin), and KOtBu, enables the unprecedented homocoupling of tetrahydroquinolines that is challenging in the ground state, expanding the chemical diversity of OHBQ derivatives.
Mone Suzuki   +2 more
wiley   +1 more source

Response to Birrell SN: Commentary on "Photosensitizing Drugs and Risk of Skin Cancer in Women". [PDF]

open access: yesPhotodermatol Photoimmunol Photomed
Nielsen K   +4 more
europepmc   +1 more source

Phosphorescent Iridium Hydrazinonicotinic Acid (HYNIC) Complexes That Bind to Prostate Specific Membrane Antigen: Potential Photodynamic Therapy of Prostate Cancer

open access: yesChemistry – A European Journal, EarlyView.
A phosphorescent iridium(III) complex has been prepared with a 6‐hydrazinonicotinic acid (HYNIC) ligand tethered to a lysine‐ureido‐glutamatic acid pharmacophore, which binds to an enzyme, called prostate‐specific membrane antigen (PSMA), which is overexpressed in prostate cancer.
La'El Kimchi   +6 more
wiley   +1 more source

Matrix‐Free Afterglow Carbon Dots: Synthetic Strategies, Luminescence Mechanisms, and Emerging Applications

open access: yesCarbon Innovation, EarlyView.
This review systematically elucidates the luminescence mechanism, synthesis methods of matrix‐free afterglow carbon dots, and their application progress in information encryption, light‐emitting diodes, sensing, bioimaging, and tumor treatment, and finally, discusses the current challenges and future development directions. ABSTRACT Afterglow materials,
Yupeng Liu   +5 more
wiley   +1 more source

Illuminating New Frontiers: Exploring the Photosensitizing Potential of Passiflora Species in Combating Methicillin-Resistant Staphylococcus aureus (MRSA) and Their Infection in Senescent Mice. [PDF]

open access: yesAdv Biol (Weinh)
Gonçalves CV   +14 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy