Results 91 to 100 of about 55,537 (299)
BMEMat, EarlyView.TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing +6 more
wiley +1 more source
Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling. [PDF]
, 2014 One challenge in biology is signal transduction monitoring in a physiological context. Intravital imaging techniques are revolutionizing our understanding of tumor and host cell behaviors in the tumor environment.
Bonora, M +9 more
core +3 more sources
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
BMEMat, EarlyView.This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
5-hydroxymethylcytosine is a key epigenetic regulator of keratinocyte stem cells during psoriasis pathogenesis [PDF]
, 2019 Epigenetic regulation is now known to play an important role in determining stem cell fate during normal tissue development and disease pathogenesis. In this study, we report loss of 5-hydroxymethylcytosine (5-hmC) mediated by ten-eleven translocation ...
Yuan, Christine Wan-Yin
core
Cryohydrocytosis: When Cold Breaks the Membrane
American Journal of Hematology, EarlyView.
Athina Ntoumaziou +5 more
wiley +1 more source
BMEMat, EarlyView.This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li +9 more
wiley +1 more source
The Effects of Pre and Post Exercise Low-Level Laser Therapy on Biochemical Markers of Skeletal Muscle Fatigue in Equines [PDF]
, 2019 Our objective was to determine whether administering low-level laser therapy before or after exercise had the greatest effect on biochemical markers of skeletal muscle fatigue in equines such as cortisol and blood lactate.
Freeman, Carson
core +2 more sources
The Dark Side of the Light: Phototherapy Adverse Effects [PDF]
, 2016 Phototherapy is a valuable therapeutic tool in Dermatology, but there may be drawbacks. Acute and long-term adverse effects, of variable severity, include skin erythema, xerosis, pruritus, blistering, altered pigmentation, photoaging, and ...
Apetato, M, Valejo Coelho, M
core +1 more source
Chemistry – A European Journal, EarlyView.Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan +3 more
wiley +1 more source
BiomedicinesBackground/Objectives: Oral mucositis (OM) is the most common acute complication among cancer patients. It initially manifests as an inflammatory process, beginning with erythema and edema of the oral mucosa, progressing to erosive lesions, and ...
Susell Parra-Rojas +4 more
doaj +1 more source