Results 151 to 160 of about 55,537 (299)
We constructed a novel excellent photodynamic drug without heavy atoms based on the conventional BODIPY photosensitizer, and then obtained a photodynamic vesicle with efficient tumor targeting (BDPM@OMVs) by bacterial extravasation. Multiple reactive oxygen species were efficiently generated under light irradiation, and the spontaneous elimination of ...
Xiang Cheng +11 more
wiley +1 more source
This study herein presents the rational design and synthesis of a series of meso‐CF3‐substituted BODIPY dyes to achieve controllable molecular aggregation and enhanced near‐infrared (NIR) phototherapeutic performance. Abstract This study herein presents the rational design and synthesis of a series of meso‐CF3‐substituted BODIPY dyes to achieve ...
Siying Gou +8 more
wiley +1 more source
Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa +9 more
wiley +1 more source
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan +10 more
wiley +1 more source
ABSTRACT The objective was to prepare guidelines to perform the current optimum treatment by organizing effective and efficient treatments of hemangiomas and vascular malformations, confirming the safety, and systematizing treatment, employing evidence‐based medicine techniques and aimed at improvement of the outcomes.
Yoshiaki Kinoshita +116 more
wiley +1 more source
The enhancing therapeutic effect of neonatal jaundice by <i>bifidobacterium</i> through regulating inflammation and gut microbiota in combination with phototherapy-a randomized controlled trial. [PDF]
Zhang F +14 more
europepmc +1 more source
Risk of Safety Events in Vitiligo Patients: A Retrospective Real‐World Data Study in the US
ABSTRACT Vitiligo is a chronic autoimmune depigmenting disease characterized by loss of pigment in the skin, hair, or both. As treatment options evolve, particularly with the emergence of oral Janus kinase inhibitors and dual Janus kinase 3/tyrosine kinase expressed in hepatocellular carcinoma family kinase inhibitor, it is essential to assess ...
Kennedy Cook +11 more
wiley +1 more source
Nanoparticles-based phototherapy systems: molecular mechanisms and clinical applications. [PDF]
Chauhan DS +8 more
europepmc +1 more source
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source

