Results 151 to 160 of about 28,629 (264)

Targeted Photo‐Induced Elimination of Tumor‐Associated Macrophages Suppresses Cancer Progression in a Murine Model

Cancer Science, EarlyView.
This study demonstrates the selective depletion of tumor‐associated macrophages (TAMs) by targeting CSF1R through near‐infrared photoimmunotherapy (NIR‐PIT). Using a combination of anti‐CSF1R Fab‐IR700 conjugates and localized light irradiation, we achieved tumor suppression and durable antitumor immunity without systemic toxicity.
Kohei Nakajima, Tomomi Uchiyama, Kazuki Funayama, Yuto Goto, Akari Mukaimine, Naoya Ieda, Mikako Ogawa   +6 more
wiley   +1 more source

Biologics and the psoriatic march: Is it time to rethink early intervention? [PDF]

J Eur Acad Dermatol Venereol
Gisondi P.
europepmc   +1 more source

Skin residual bilirubin volume: a physiologically informed framework for transcutaneous bilirubin interpretation in neonates. [PDF]

Front Pediatr
Amadi HO.
europepmc   +1 more source

Ultraviolet Phototherapy

Journal of the Royal College of Physicians of London, 1997
openaire   +2 more sources

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Phototherapy, Morbidity, and Mortality in Very Preterm Newborns.

JAMA Netw Open
Deschmann E, Håkansson S, Söderling J, Norman M.   +3 more
europepmc   +1 more source

Comparison of Phototherapy and Exchange Transfusion Thresholds According to the Turkish Neonatology Society and the 2022 American Academy of Pediatrics Guidelines in Neonates with Indirect Hyperbilirubinemia. [PDF]

Children (Basel)
Keskindil D, Alkan Ozdemir S, Çalkavur Ş, Yildirim TG.   +3 more
europepmc   +1 more source

Clinical and Genetic Profile of One Molecularly Confirmed and One Clinically Suspected Case of LZTR1‐Related Noonan Syndrome

Clinical Genetics, EarlyView.
This study illustrates the phenotypic variability of LZTR1‐related Noonan syndrome type 10 in two pediatric patients, including presentations without congenital heart defects. The findings emphasize the importance of whole‐exome sequencing and longitudinal re‐evaluation of variants of uncertain significance in achieving accurate diagnosis.
Karolina Skrzyńska, Barbara Kalina‐Faska, Ewa Błaszczyk, Aneta Gawlik‐Starzyk   +3 more
wiley   +1 more source

Molecularly engineered BODIPY photosensitizers for combined cancer phototherapy and immunotherapy. [PDF]

Front Pharmacol
Wang H, Zhang Y, Zhou M.
europepmc   +1 more source

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp, Hanna Schratter, Johanna Auer, Gerold Schwantzer, Maximilian Lammer, Philipp Hinteregger, Ines Vergeiner, Robert Gruber, Peter Wolf, Angelika Hofer   +9 more
wiley   +1 more source