Results 51 to 60 of about 26,189 (167)
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.This work presents a thermodynamically programmable nanoplatform based on calixarenes that enables precise, tunable drug loading and release with broad applicability. Across diverse drugs and ratios, both loading and delivery matched preset values with > 95% accuracy in cells and tumors.
Yu‐Chen Pan +9 more
wiley +2 more sources
Recent Advances in High‐Entropy Nanozymes: From Fabrication to Applications
Advanced Science, EarlyView.To highlight key achievements and clarify the current landscape of high‐entropy nanozymes (HEAzymes), this review summarizes state‐of‐the‐art developments ranging from thermodynamically and kinetically controlled synthetic strategies; enzyme‐like catalytic types, catalytic characteristics, and underlying mechanisms; to their antioxidative, therapeutic,
Yongjian Ai +8 more
wiley +1 more source
Advanced Science, EarlyView.An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu +11 more
wiley +1 more source
Advanced Science, EarlyView.A carrier‐free peptide‐guided PSP@IR‐CF3 nanofiber system integrates PD‐L1 targeting and photothermal immunotherapy for enhanced cancer treatment. By revealing PTIT‐induced activation of the HSP70/AKT/mTOR pathway and incorporating mTOR inhibition, this strategy effectively overcomes therapeutic resistance and prevents tumor recurrence, providing a ...
Xinyu Zhang +11 more
wiley +1 more source
Membrane‐Targeted Nanoparticles for Neuronal Photomodulation
Advanced Science, EarlyView.Immobilizing gold nanoparticles on the neural interface using a bioorthogonal approach generates localized heat upon exposure to near‐infrared light, temporarily inhibiting primary neuronal activity without damaging the cells. This precise placement and retention of nanoparticles at the cell membrane expand the strategies for non‐invasive neural ...
Ane Escobar +9 more
wiley +1 more source
Programable Acoustic Single‐Cell Manipulation With Model‐Free Machine Learning
Advanced Intelligent Systems, EarlyView.Closed‐loop control with ultrasound enables precise, noninvasive manipulation of individual cells inside a microfluidic device using a model‐free reinforcement learning‐inspired algorithm, achieving 2D control using a single piezoelectric transducer.
Alexander Edthofer +3 more
wiley +1 more source
HER2-targeted multifunctional gold nanorods for imaging-guided combined chemotherapy and photothermal therapy. [PDF]
Discov NanoLee SM, Park H, Han J, Park YB, Yoo KH.
europepmc +1 more source
Advanced Intelligent Systems, EarlyView.Wearable sensors usually warn through sight or sound, channels that become unreliable under protective equipment or in noise. Reverse haptic alerting inverts this flow: Stimuli‐responsive materials convert chemical and biological signals into cues felt through the skin, while a machine‐learned digital twin of tactile perception personalizes the body ...
Hwanhee Yoo +5 more
wiley +1 more source
Gold Nanorod-Based USP8 Inhibition Combined with Photothermal Therapy Enhances Antitumor Efficacy in Gastric Cancer. [PDF]
Int J NanomedicineZheng Q, Wang H, Huang J.
europepmc +1 more source