Results 101 to 110 of about 26,819 (226)

Benchmark of Open‐Access Star‐Allele Callers to Accurately Assess Haplotypes and Phenotypes in Pharmacogenetic Studies

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 520-530, August 2026.
Genetic polymorphisms are common in pharmacogenes, with sometimes important implications for drug metabolism. Assessing the correct enzyme phenotype from genetic data is thus a crucial step into the development of personalized medicine. Many bioinformatics star‐allele callers have been developed for this purpose of identifying the correct star alleles ...
Marc B. Gros‐La‐Faige, Emmanuelle Génin, Anthony F. Herzig   +2 more
wiley   +1 more source

An Efficient Quasi‐Static Condensation‐Based Framework for Seismic Analysis of Multi‐Supported Secondary Structures

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 10, Page 2466-2485, August 2026.
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang, Fengze Li, Xudong Zhi, Nawawi Chouw, Rong Zhang, Feng Fan   +5 more
wiley   +1 more source

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

Scalable discovery of homomeric protein–protein interactions from cross‐linking mass spectrometry data with CLAUDIO 2.0

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Cross‐linking mass spectrometry (XL‐MS) is a powerful biochemical approach for residue‐level characterization of protein structures and interactions under near‐native conditions. The growing scale of XL‐MS datasets demands scalable analysis pipelines that capture signals often overlooked in conventional workflows, including homomeric ...
Tobias Löser, Alexander Röhl, Markus Baier, Andrei Lupas, Oliver Kohlbacher, Hadeer Elhabashy   +5 more
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, Volume 40, Issue 8, Page 5005-5015, August 2026.
ABSTRACT Ashwagandha ( Withania somnifera ) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Establishing a Specialty Bipolar Clinic: The National Network of Depression Centers Consensus Recommendations

Bipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Objective To provide expert recommendations for the development of a specialty bipolar clinic that promotes best clinical practices for the delivery of safe and effective care. Methods Members of the National Network of Depression Centers (NNDC) Bipolar Clinics Work Group met in a series of 1‐h monthly video calls over 18 months to discuss all
Christopher D. Schneck, Jorge R. C. Almeida, David J. Bond, Katherine E. Burdick, Mark A. Frye, Fernando S. Goes, Rebekah S. Huber, Rodrigo Machado‐Vieira, Pamela Mahon, Melvin G. McInnis, John Nurnberger, Dost Ongur, Michael J. Ostacher, Sagar V. Parikh, Kristin S. Raj, Matteo Respino, Barbara W. Schweizer, Jair C. Soares, Sarah H. Sperry, Aimee E. Sullivan, Trisha Suppes, Marin Veldic, Peter P. Zandi, J. Raymond DePaulo   +23 more
wiley   +1 more source

Uncovering correlates of decline and critical refuges for a threatened terrestrial mammal

Conservation Biology, Volume 40, Issue 4, August 2026.
Abstract Globally, the geographic ranges of numerous species are contracting. Identifying spatiotemporal patterns of threat impact can illuminate why species decline in some parts of their range but persist in others. We developed a correlative approach to identify species’ response thresholds and locate ecological refuge areas associated with ...
Natalya M. Maitz, Michelle S. Ward, Jonathan R. Rhodes, Ben C. Scheele, Hugh P. Possingham, Diana O. Fisher   +5 more
wiley   +1 more source

Semaglutide Injection in Indian Patients With Type 2 Diabetes Mellitus: A Randomised, Phase III, Active‐Controlled Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7094-7103, August 2026.
ABSTRACT Aim To evaluate the efficacy, safety and immunogenicity of semaglutide injection (synthetic) (Test group) compared with the Reference semaglutide injection [Ozempic, (Reference group)] in Indian patients with Type 2 diabetes mellitus (T2DM).
Unnikrishnan Ambika Gopalakrishnan, Ameya Sudhakar Joshi, Richa Giri, Shalin Jagdeep Shah, Jitendra Shukla, Sanjiv Maheshwari, Rekha M. Chowdaiah, Manish Kumar Singh, Aditya Srirang Bari, Niranjan Pandurang Pathak, Akash Nitinbhai Shah, Shweta Bhandari, Ambanna Gowda, Ambrish Chandrappa, Pravin Dinkar Supe, Bharat Das, Prabhat Kumar Sharma, Mehul Kalubhai Virani, Prakash Harishchandra Kurmi, Gayatri Amit Ghanekar, Mani Deepathi Dasari, Banshidhar Sahoo, Sanjay Kumar Jangid, Prakash Sadashiv Shende, Sandesh Sahebarao Patil, Avinash Narayan Kumbhar, Shrikant Vishnu Deshpande, Madhusudhan Chennappa, Nitesh Chandubhai Patel, Dipesh Sonawane, Dipak Patil, Sucheta Pandit, Pravin Ghadge, Suyog Mehta   +33 more
wiley   +1 more source

Pattern of height and weight development in a large cohort of underage Chinese pseudohypoparathyroidism patients from a single center. [PDF]

Endocr Connect
Yang Y, Song A, Du H, Jiang Y, Li M, Xia W, Xing X, Wang O, Pan H.   +8 more
europepmc   +1 more source

A Dialogic Participatory Model Between Professionals and Patients for the Co‐Creation of Transitioning Care Management Programmes in Rare Bone Diseases

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Introduction Rare diseases are a group of heterogeneous conditions affecting fewer than 5 per 10,000 individuals in Europe, with rare bone diseases representing a clinically significant subgroup. Multiple osteochondromas, Ollier disease and Maffucci syndrome are multifocal benign rare disorders, characterised by bone deformities, functional ...
Marina Mordenti, Silvia Forni, Eleonora Grippa, Maria Cecilia la Forgia, Davide Scognamiglio, Manila Boarini, Gabriella Massa, Andrea Romeo, Alessandro Sergi, Luca Sangiorgi, Transitioning Care Management Working Group (TCM WG), Giovanni Beltrami, Domenico Campanacci, Nunzio Catena, Mauro Celli, Marta Cervo, Leonardo D'Agruma, Gian Luigi Federico, Giovanni Gallone, Michela Veronika Gonfiantini, Laura Masi, Maria Beatrice Michelis, Osvaldo Palmacci, Annabruna Ronchetti, Paolo Trezza   +24 more
wiley   +1 more source