Results 51 to 60 of about 4,429 (182)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ETHNIC AUTHENTICATION OF MOVCYA IN PHRASEOLOGY UNITS EXCLAMATION OF PROSE MARIA MATIOS

Записки з українського мовознавства, 2017
This article explores exclamation phraseological units as verbalizatory ethnic identification hutsuls and Bukovina in prose Mary Matios. It is established that the structure of the phraseology reflected hutsuls religious stereotypes and Bukovina, piety ...
Т. О. Євтушина
doaj   +1 more source

Les débuts de la phraséologie et les premières « phraséologies historiques » italo-françaises

Linguistik Online, 2022
Phraseological studies are prospering, as there have been many important publications over the last years. However, while most researchers date phraseology studies back to Charles Bally (1909), they have a long tradition that has been ignored for years.
Erica Autelli
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Typological Structure of German Phraseology Outside Germany. Quantitative Parameters

Journal of Vasyl Stefanyk Precarpathian National University, 2016
The article deals with the modern theoretical concept in study of the variation of German phraseology abroad Germany. It is based on the synthesis of the theory of equal-righted pluricentrism with the new achievements of the cognitive linguistics.
О. Ya. Ostapovych
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

PHRASEOLOGICAL PREPOSITION AS A STRUCTURAL COMPONENT OF PHRASEOLOGISMS-UNION

, 2022
In this article structural features of phraseological prepositions and structural component of phraseologisms-union will be discussed broadly with clear illustrations which is one of the quastionable and tough side of English language.
openaire   +2 more sources

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Cando chove e dá o sol... ¿Un fraseoloxismo internacional poliédrico? [PDF]

Cadernos de Fraseoloxía Galega, 2007
Análise da fraseoloxía galega relacionada coa simultaneidade de dous fenómenos antitéticos (a choiva e o brillo do sol), contextualización na fraseoloxía internacional e intento de interpretación. Reclámase a cooperación da fraseoloxía e a antropoloxía
Xesús Ferro Ruibal
doaj  

Способи представлення лінгвокультурологічної інформації у фразеологічних словниках (на матеріалі ономастичної фразеології) [PDF]

Studia Slavica
The article analyzes the experience of Slavic phraseological lexicography from the point of view of the representation of the linguistic potential of phraseology, the necessity of developing separate phraseological lexicographic directions ...
Галина Кузь
doaj   +1 more source