Results 101 to 110 of about 1,167,222 (309)

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

Advanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo, Seong‐Gook Kang, Kunlun Huang, Tao Tong   +3 more
wiley   +1 more source

A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution

, 2022
Xavier Grau‐Bové, Cristina Navarrete, Cristina Chiva, Thomas Pribasnig, Meritxell Antó, Guifré Torruella, Luis Javier Galindo, B. Franz Lang, David Moreira, Purificación López‐García, Iñaki Ruiz‐Trillo, Christa Schleper, Eduard Sabidó, Arnau Sebé-Pedrós   +13 more
openalex   +2 more sources

Coupling Nitrogenous Organic Wastewater Treatment and Biorefinery via N‐Cycling Bacterium

Advanced Science, EarlyView.
The vast reservoir of nitrogenous organic pollutants in industrial wastewaters can serve as untapped carbon‐nitrogen resources. This study employs the newly discovered Paracoccus sp. ZQW‐1 as a versatile chassis to simultaneously achieve N‐methylpyrrolidone (NMP) wastewater depuration and polyhydroxybutyrate (PHB) synthesis.
Ziqian Wang, Chunyu Du, Guanyu Zheng, Dahu Ding   +3 more
wiley   +1 more source

Mitochondrial Genome Analysis of Babesia ovis (Apicomplexa: Babesiidae) Endemic in Sheep in Türkiye

Veterinary Sciences
This study presents the first comprehensive analysis of the mitochondrial genome of Babesia ovis, a significant pathogen in ovine babesiosis in Türkiye. The B.
Mehmet Can Ulucesme, Munir Aktas, Sezayi Ozubek   +2 more
doaj   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Estimating the Current Routes of Transmission in HIV-1 F1 Subtype Infected Persons in Romania: Differences Between Self-Reporting and Phylogenetic Data

Pathogens
Monitoring the HIV epidemic in Romania has proven challenging due to many factors, including the reluctance of newly diagnosed patients to disclose relevant epidemiological aspects during the clinical interview, such as sexual orientation or the ...
Robert Hohan, Simona Paraschiv, Ionelia Nicolae, Dan Oțelea   +3 more
doaj   +1 more source

Phylogenetic analysis of Magnoliales and Myristicaceae based on multiple data sets: implications for character evolution [PDF]

, 2003
Hervé Sauquet, James A. Doyle, Tanya Scharaschkin, Thomas Borsch, Khidir W. Hilu, Lars W. Chatrou, Annick Le Thomas   +6 more
openalex   +1 more source

HIV phylogenetics [PDF]

BMJ, 2007
Pillay, D., Rambaut, A., Geretti, A. M., Brown, A. J. L.   +3 more
openaire   +4 more sources

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Novel cycloviruses identified by mining human blood metagenomic data show close relationship to those from animals

Frontiers in Microbiology
The family Circoviridae includes the genera Circovirus and Cyclovirus. Cycloviruses have been found in serum samples from chronic HBV, HCV, or HIV-infected individuals as well as asymptomatic blood donors.
Yuanqing Wang, Yuanqing Wang, Xiaojie Jiang, Yuan Xi, Siqi Wei, Songyi Ning, Wen Zhang, Wen Zhang   +7 more
doaj   +1 more source