Results 151 to 160 of about 1,167,222 (309)
CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis
Advanced Science, EarlyView.This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin +14 morewiley +1 more sourceGut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation
Advanced Science, EarlyView.Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract
Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao +10 morewiley +1 more sourceHigher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation
Advanced Science, EarlyView.Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...Benjámin Kovács, Durga Prasad, Vic De Roo, Matthias Vanheede, Penthip Muangkaew, Annemieke Madder, Monica Höfte, René De Mot, Niels Geudens, José C. Martins +9 morewiley +1 more sourceMicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis
Advanced Science, EarlyView.Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.Ludi Wang, Hexing Han, Yufeng Liu, Zhiyuan Ning, Yujie Ma, Haidan Wang, Jinling Xu, Qiansheng Huang, Wenjuan Cui, Yuanchun Zhou, Yang Gao, Bin Wang, Yi Du +12 morewiley +1 more sourceTargeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity
Advanced Science, EarlyView.Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang +12 morewiley +1 more sourcePhylogenetics
Scholarpedia, 2008 J. Howard Frank, J. Howard Frank, Michael C. Thomas, Allan A. Yousten, F. William Howard, Robin M. Giblin-davis, John B. Heppner, Robert L. Zuparko, Norma E. Sánchez, María G. Luna, Marta Goula, John B. Heppner, Andrey N. Alekseev, Rosalind R. James, John L. Capinera, Phyllis G. Weintraub, David Horton, J. Howard Frank, Kenneth W. Mccravy, David G. Riley, David C. Marshall, Cyrus Abivardi, Marjorie A. Hoy, Efat M. Abou-fakhr hammad, Jason G. Froeba, David Legg, Heather J. Mc Auslane, Qiao Wang, Cyrus Abivardi, Seth Bybee, Menachem J. Berlinger, Sarah Lebiush-mordechi, Harold A. Denmark, J. Howard Frank, Whitney Cranshaw, John L. Capinera, John B. Heppner, Chris Asaro, Erik Christiansen, William J. Roltsch, Dale E. Meyerdirk, Lewis B. Coons, Marjorie Rothschild, Minos E. Tzanakakis, Pauline O. Lawrence, Alfred G. Wheeler, Thomas J. Henry, Russell F. Mizell, Partricia A. Mizell, John B. Heppner, Lois B. O’ brien, Menachem J. Berlinger, Anthony Rossi, Wayne B. Hunter, Charles Vincent, Gérald Chouinard, Tracy Leskey, Deborah L. Matthews, Peter G. Kevan, Antonio Felicioli, Mauro Pinzauti, Olle Pellmyr, John T. Trumble, Danel B. Vickerman, Cyrus Abivardi, Robert McSorley, K. K. Verma, John L. Capinera, Peter H. Adler, Igor Uspensky, Donald W. Hall, John L. Capinera, Juan M. Alvarez, John L. Capinera, Eugene J. Gerberg, Lawrence E. Hurd, Lawrence E. Hurd, Patrick De Clercq, John B. Heppner, J. Howard Frank, Lawrence I. Gilbert, Robert Rybczynski, Christopher Tipping, James H. Tsai, Philip Weinstein, David Slaney, Peter H. Adler, Zeyaur R. Khan, John A. Pickett, John B. Heppner, Cyrus Abivardi, Katie Goodman, Kenneth W. McCravy, Andrei Sourakov +93 more +4 more sources