Results 61 to 70 of about 481,099 (261)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The complete chloroplast genome of Strobilanthes biocullata (Acanthaceae)

Mitochondrial DNA. Part B. Resources, 2021
Strobilanthes biocullata is a plietesial species endemic to China. The complete chloroplast genome (cp genome) of S. biocullata was sequenced for the first time. The cp genome of S. biocullata is 144,012 bp in length.
Qin Wang, Sunan Huang, Xin Chen, Yunfei Deng   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Amphibians and Reptiles Exhibit Different Ecological and Evolutionary Spatial Patterns in the Amazon Basin

Ecology and Evolution
Understanding spatial variability in ecological and evolutionary patterns is key to Amazonian biodiversity conservation. This study examined taxonomic, phylogenetic, and functional diversity across amphibians and reptiles, assessing the influence of ...
Jhon Jairo López‐Rojas, Diego Henrique Santiago, Mirco Solé, Ricardo Lourenço‐de‐Moraes   +3 more
doaj   +1 more source

Plastome Sequences Help to Resolve Deep-Level Relationships of Populus in the Family Salicaceae

Frontiers in Plant Science, 2019
Populus, a core genus of Salicaceae, plays a significant ecological role as a source of pioneer species in boreal forests. However, interspecific hybridization and high levels of morphological variation among poplars have resulted in great difficulty in ...
Dan Zong, Dan Zong, Peihua Gan, Peihua Gan, Anpei Zhou, Anpei Zhou, Yao Zhang, Yao Zhang, Xinlian Zou, Xinlian Zou, Anan Duan, Anan Duan, Anan Duan, Yu Song, Yu Song, Chengzhong He, Chengzhong He, Chengzhong He   +17 more
doaj   +1 more source

DNA Barcoding of Cardinalfish (Apogonidae) in Gilimanuk Bay, Bali, Indonesia

Jurnal Ilmiah Perikanan dan Kelautan, 2023
The Apogonidae is estimated to consist of nearly 300 fish species, most of which inhabit coral reef areas. The lack of distinctive body markings and overlapping species distribution makes species assignment challenging.
I Nyoman Giri Putra Putra, Gede Surya Indrawan, Elok Faiqoh   +2 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Phylogenetic Web Profiler [PDF]

Bioinformatics, 2003
Abstract Summary: Phylogenetic Web Profiler (PWP) is a web-based service designed to perform phylogenetic profiling of proteins against genomes. The current version offers a selection of 63 completed genomes and available plasmids as annotated in the PEDANT genome database.
Philip Wong, Grigory Kolesov, Dmitrij Frishman, Walid A. Houry   +3 more
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Format for Phylogenetic Placements

PLoS ONE, 2012
We have developed a unified format for phylogenetic placements, that is, mappings of environmental sequence data (e.g. short reads) into a phylogenetic tree. We are motivated to do so by the growing number of tools for computing and post-processing phylogenetic placements, and the lack of an established standard for storing them.
Matsen, Frederick A., Hoffman, Noah G., Gallagher, Aaron, Stamatakis, Alexandros   +3 more
openaire   +6 more sources