Results 11 to 20 of about 330 (99)
Abstract Protein engineers aim to discover and design novel sequences with targeted, desirable properties. Given the near limitless size of the protein sequence landscape, it is no surprise that these desirable sequences are often a relative rarity. This makes identifying such sequences a costly and time‐consuming endeavor. In this work, we show how to
Trevor S. Frisby +1 more
wiley +1 more source
On the role of metaheuristic optimization in bioinformatics
Abstract Metaheuristic algorithms are employed to solve complex and large‐scale optimization problems in many different fields, from transportation and smart cities to finance. This paper discusses how metaheuristic algorithms are being applied to solve different optimization problems in the area of bioinformatics. While the text provides references to
Laura Calvet +3 more
wiley +1 more source
Selection on standing genetic variation mediates convergent evolution in extremophile fish
Abstract Hydrogen sulfide is a toxic gas that disrupts numerous biological processes, including energy production in the mitochondria, yet fish in the Poecilia mexicana species complex have independently evolved sulfide tolerance several times. Despite clear evidence for convergence at the phenotypic level in these fishes, it is unclear if the repeated
Kara Ryan +5 more
wiley +1 more source
Pitfalls of using sequence databases for heterologous expression studies – a technical review
Abstract figure legend Projects involving heterologous gene expression are often characterised by similar steps. Initially, database research (A) is necessary to retrieve information of full or partial sequences of a gene of interest. A multitude of genome assemblies are annotated and deposited in public databases or are available for refined search ...
Stephan Maxeiner +2 more
wiley +1 more source
Abstract Ecological networks such as plant–pollinator systems and food webs vary in space and time. This variability includes fluctuations in global properties such as the total number and intensity of interactions in the network but also in the number and intensity of local (i.e. node level) species interactions.
Tancredi Caruso +3 more
wiley +1 more source
A branching process approach to level‐k phylogenetic networks
Abstract The mathematical analysis of random phylogenetic networks via analytic and algorithmic methods has received increasing attention in the past years. In the present work we introduce branching process methods to their study. This approach appears to be new in this context.
Benedikt Stufler
wiley +1 more source
Summary The strigolactone (SL) class of phytohormones shows broad chemical diversity, the functional importance of which remains to be fully elucidated, along with the enzymes responsible for the diversification of the SL structure. Here we explore the functional evolution of the highly conserved CYP711A P450 family, members of which catalyze several ...
Marcos H. Vinde +10 more
wiley +1 more source
The to‐and‐fro of social interaction—termed enchrony—has been understudied in the language sciences, but new developments are changing how we think about the relation between language and mind. Abstract What are the properties of mind that make language the way it is, and languages the way they are? To answer those questions, it is necessary to look at
N. J. Enfield
wiley +1 more source
This work addresses a novel group of Sebacinales mycorrhizal fungi being considered for development as inoculants in managed ecosystems because of their potential access to nutrients in soil organic matter. By comparing the diversity, distributions, and abundances of the Sebacinales with the more common arbuscular mycorrhizal fungi in switchgrass, a ...
Marissa R. Lee, Christine V. Hawkes
wiley +1 more source
When colonies first evolve from solitary ancestors, the life‐history strategy of the colony remains constrained by the life‐history strategies of the individual modules within the colony until a new polymorph type evolves. Colonies can evolve further strategies by regulating the frequencies of body types within the colony.
Carl Simpson
wiley +1 more source

