Results 181 to 190 of about 2,710,018 (298)

Beneath the Ground: Phylogenetic Position and Morphological Characteristics of <i>Ityogonimus ocreatus</i> (Goeze, 1782) (Digenea: Brachylaimidae), a Parasite of European Moles. [PDF]

Biology (Basel)
Kirillova NY, Kirillov AA, Shchenkov SV, Gorodilova EY.   +3 more
europepmc   +1 more source

Discovery of Regulatory Elements by a Computational Method for Phylogenetic Footprinting

, 2002
Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of orthologous regulatory regions from multiple species. It does so by identifying the best conserved motifs in those orthologous regions.
For Phylogenetic Footprinting, Martin Tompa, Mathieu Blanchette   +2 more
core  

Differential Water Networks Guide Selectivity Optimization of a Cell Active BPTF Inhibitor in Neuroblastoma

Angewandte Chemie, EarlyView.
BZ2 is a second‐generation Bromodomain PHD finger Transcription Factor (BPTF) inhibitor with improved selectivity over Class I and Class IV BRD off‐targets identified in our previously reported inhibitor, BZ1. Structural analyses reveal that water network engagement is key to this selectivity.
Kesavan Babu, Chun‐Ju Tsou, Sourav Das, Liying Fan, Anasuya Pal, Molly Sneddon, Timothy R. Stachowski, Priyanka Samanta, Stanley Nithianantham, Caroline Buchholz, Shi Zhang, Xiang Fu, Rahul S. Kathayat, Wenwei Lin, Yongtao Li, Lei Yang, Taosheng Chen, Marcus Fischer, Anang A. Shelat, William C. K. Pomerantz   +19 more
wiley   +2 more sources

The complete chloroplast genome sequence and phylogenetic position of <i>Causonis japonica</i> (Thunb.) Raf. (Vitaceae). [PDF]

Mitochondrial DNA B Resour
Zheng C, Sun T, Zheng J, Yu S, Zhu W, Xiong C.   +5 more
europepmc   +1 more source

A Conserved Isoleucine Gates the Diffusion of CO and O2 to the Active Site of NiFe CO‐Dehydrogenase

Angewandte Chemie, EarlyView.
A combination of protein film electrochemistry and site‐directed mutagenesis shows that isoleucine 563 (numbering of Thermococcus sp. AM4) gates the arrival of both CO and O2 to the active site of the nickel‐iron CO dehydrogenases. Mutations at this position increase the resistance to O2 at the cost of a slower reaction with CO.
Laura Opdam, Marta Meneghello, Chloé Guendon, Jade Chargelègue, Andrea Fasano, Aurore Jacq‐Bailly, Christophe Léger, Vincent Fourmond   +7 more
wiley   +2 more sources

Three New Mitochondrial Genomes of Neritidae (Gastropoda, Neritimorpha) From China and Insights Into Their Phylogenetic Position. [PDF]

Ecol Evol
Rao Y, Meng Y, Zeng S, Yang D.
europepmc   +1 more source

Phylogenetic position and mitochondrial genome evolution of "orphan" eukaryotic lineages. [PDF]

iScience
Zlatogursky V, Boscaro V, Lax G, Wanntorp M, Pohl N, Burki F, Keeling PJ.   +6 more
europepmc   +2 more sources

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

The complete mitochondrial genome and phylogenetic position of <i>Triplophysa qiubeiensis</i> (Cypriniformes: Nemacheilidae). [PDF]

Mitochondrial DNA B Resour
Chen Y, Zhu Y, Wang Y, Wang D.
europepmc   +1 more source

Mitochondrial genome of <i>Scutiger boulengeri</i> (Anura, Megophryidae) reveals an exceptionally expanded non-coding region and its phylogenetic position within Megophryidae. [PDF]

Zookeys
Wang WT, Zhang FH, Wang R, Zhang XZ.
europepmc   +1 more source