Results 41 to 50 of about 184,125 (260)

Phylogenetic Position of African Punctoid Snails (Stylommatophora, Punctoidea, Trachycystinae)

Taxonomy, 2022
The punctoid land snail family Charopidae, as currently defined, is a paraphyletic assemblage of taxa with Gondwanan distribution. It is represented in Africa largely by the pinwheels (genus Trachycystis and allies) and afrodontas (genus Afrodonta and ...
Rodrigo Brincalepe Salvador
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

What is the phylogenetic position of Cryptosporidium? [PDF]

International Journal of Systematic and Evolutionary Microbiology, 2000
The phylogenetic position of Cryptosporidium is elusive. Although previous studies based solely upon small-subunit (SSU) rRNA sequences suggested that the genus was an early emerging lineage among the Apicomplexa, bootstrap support for this placement was low.
G, Zhu, J S, Keithly, H, Philippe
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The complete mitochondrial genome of the blackskin catfish (Clarias meladerma: Clariidae) from Rokan River, Riau, Indonesia

Mitochondrial DNA. Part B. Resources
Clarias meladerma Bleeker, 1846, a native catfish species in Indonesia belonging to the family Clariidae. The present study the complete mitochondrial genome sequence of C. meladerma from the Rokan River was sequenced by using next-generation sequencing,
Huria Marnis, Khairul Syahputra, Bambang Iswanto, Imam Civi Cartealy, Sularto, Jadmiko Darmawan, Erma Primanita Hayuningtyas, Rahmat Hidayat, Arsad Tirta Subangkit, Arianto   +9 more
doaj   +1 more source

Phylogenetic Position of the Genus Manunema (Nematoda, Plectida, Leptolaimidae)

Diversity, 2023
During an investigation of a natural sandy beach on Jeju Island, South Korea, a species of marine nematode belonging to the rare genus Manunema was discovered and is now being reported.
Raehyuk Jeong, Alexei V. Tchesunov
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The complete mitochondrial genome of Lutjanus bohar (Actinopterygii, Lutjanidae)

Mitochondrial DNA. Part B. Resources
Lutjanus bohar Forsskål 1775, a large reef-associated fish species, is widely distributed across tropical and subtropical waters and is recognized as a significant commercial fishery resource. Here, the complete mitochondrial genome of L.
Xin Huang, Xiao Li, Shitao Fang, Qi Zhou, Qing Dong, Hongjie Long, Jingyi Chen, Yingrui Xu, Dan Mu, Xunchao Cai   +9 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Phylogenetic Position of the Bacteria

Botanical Gazette, 1921
The subject of the phylogenetic position of the bacteria has been approached by many students. Early workers came to no more diverse conclusions than do modern ones. Some investigators, for example NXGELI (24) and GdTSCHLICH (14), have placed the bacteria with the fungi, while COHN (9), MIGULA (22), and SACHS (26) placed them with the algae.
openaire   +2 more sources