Results 151 to 160 of about 1,097,195 (292)
Advanced Science, EarlyView.By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu +11 more
wiley +1 more source
Common Methods for Phylogenetic Tree Construction and Their Implementation in R
BioengineeringA phylogenetic tree can reflect the evolutionary relationships between species or gene families, and they play a critical role in modern biological research.
Yue Zou +6 more
doaj +1 more source
Advanced Science, EarlyView.The transcription factor MoSR governs DMI fungicide sensitivity in Magnaporthe oryzae through dual regulation of ergosterol biosynthesis and the detoxification enzyme MoDde1. Targeting MoDde1 via a small‐molecule inhibitor or host‐induced gene silencing enhances DMI efficacy against rice blast, offering a sustainable disease management strategy ...
Fan‐Zhu Meng +10 more
wiley +1 more source
MathematicsRecent developments of Normalized Compressed Distance (NCD) matrices show potential to become a widely used method to develop phylogenetic trees among a group of organisms.
Damian Moreno +3 more
doaj +1 more source
Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures
Advanced Science, EarlyView.ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels +12 more
wiley +1 more source
PLoS Computational BiologyBayesian phylogenetic analysis with MCMC algorithms generates an estimate of the posterior distribution of phylogenetic trees in the form of a sample of phylogenetic trees and related parameters.
Lars Berling +5 more
doaj +1 more source
Advanced Science, EarlyView.Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang +18 more
wiley +1 more source
Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae
Angewandte Chemie, EarlyView.The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray +4 more
wiley +2 more sources
, 2018 All phylogenetic trees inferred in the course of this project.
Schwentner, Martin +7 more
core +1 more source
Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics
Advanced Science, EarlyView.Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan +5 more
wiley +1 more source