Results 81 to 90 of about 478,847 (346)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

DNA taxonomy reveals high species diversity among the stygobiont genus Metastenasellus (Crustacea, Isopoda) in African groundwater [PDF]

Subterranean Biology
This study aimed to explore the species diversity within the isopod genus Metastenasellus in Benin and Cameroon. Compared to other parts of the world, the described diversity of stygobiotic crustaceans in Africa is low due to a dearth of studies and ...
Moïssou Lagnika, Raoul Polycarpe Tuekam Kayo, Gontran Sonet, Jean-François Flot, Patrick Martin   +4 more
doaj   +3 more sources

Emotion and Phylogeny.

The Japanese Journal of Physiology, 1999
Gentle handling of mammals (rats, mice) and lizards (Iguana), but not of frogs (Rana) and fish (Carassius), elevated the set-point for body temperature (i.e., produced an emotional fever) achieved only behaviorally in lizards. Heart rate, another detector of emotion in mammals, was also accelerated by gentle handling, from ca. 70 beats/min to ca.
openaire   +4 more sources

Phylogeny of Echinoderm Hemoglobins [PDF]

PLOS ONE, 2015
Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and α-globin/β-globin tetramer hemoglobin, and several minor groups.
Christensen, AB, Herman, JL, Elphick, MR, Kober, KM, Janies, D, Linchangco, G, Semmens, DC, Bailly, X, Vinogradov, SN, Hoogewijs, D   +9 more
openaire   +6 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Deep‐sea caridean shrimps collected from the South China Sea with emphasizing their phylogenetic relationships

Ecology and Evolution
Despite the high biological and ecological diversity of the South China Sea, limited research has been conducted on the deep‐sea species diversity of caridean shrimps.
Zhibin Gan, Xuefeng Fang, Xinzheng Li
doaj   +1 more source

Identifications of Common Species and Descriptions of Two New Species of Siphonaria (Mollusca: Gastropoda) in China

Biology
The genus Siphonaria G [...]
Guochen Zang, Jiahui Wang, Peizhen Ma, Cui Li, Ya Chen, Zeyu Tang, Haiyan Wang   +6 more
doaj   +1 more source

Solving the Persistent Phylogeny Problem in polynomial time [PDF]

arXiv, 2016
The notion of a Persistent Phylogeny generalizes the well-known Perfect phylogeny model that has been thoroughly investigated and is used to explain a wide range of evolutionary phenomena. More precisely, while the Perfect Phylogeny model allows each character to be acquired once in the entire evolutionary history while character losses are not allowed,
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Integrative Taxonomy Reveals New Insights into the Species Validity of the Neocaridina davidi-N. denticulata-N. heteropoda Complex and Mitogenomic Phylogeny of Caridean Shrimps

Current Issues in Molecular Biology
The genus Neocaridina, originating from East Asia and representing a small-size landlocked shrimp group of the family Atyidae, is an important group of ornamental shrimps and plays significant ecological roles in their natural habitats.
Mei Yang, Xiaodong Cui, Xinzheng Li, Dong Dong, Xianjiang Kang, Zhibin Gan   +5 more
doaj   +1 more source