Results 101 to 110 of about 331,521 (282)

The Informational Nature of Consciousness and the Physical Truth of Life: A Unified Explanation Based on Motion Forms and Spatial Information Field

open access: yes
Based on the core positions of physicalism and information theory, combined with modern neuroscience advances and the spatial information field theory within the framework of unified field theory, this paper systematically demonstrates that the essence of consciousness and soul is the ordered motion form of charged particles in the human brain, whose ...
openaire   +3 more sources

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

The village and the city: a diagnostic study of the spatial embedding patterns in villages absorbed by cities in Bahrain

open access: yes, 2009
During the growth of cities villages are frequently absorbed into the fabric of that conurbation. But what are the consequences of this? To what extent and how well do these villages become part of the overall fabric of the city?
AL-Ghatam, W.
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Influence of Heat Sources and Relaxation Time on Temperature Distribution in Tissues

open access: yesInternational Journal of Applied Mechanics and Engineering, 2014
In the present study, the temperature fluctuations in tissues based on Penne’s bio-heat transfer equation is investigated by applying the Laplace and Hankel transforms.
S. Sharma, K. Sharma
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Socio-spatial isomorphism

open access: yes, 2012
It is contended that space can act as a metaphor for social relationships. The thesis draws on schema theory from cognitive psychology to explain how the affective qualities of social stimuli serve to bias the 'cognitive maps' of individuals ...
MacBride, S. J. C.
core  

Design of spatial interfaces for engineering assembly within a virtual environment for automotive design [PDF]

open access: yes, 2003
This thesis presents studies on the design of a novel two-handed spatial interface for engineering assembly, informed by a number of qualitative studies using a realistic assembly model within a fully working virtual environment (VE).
Liu, Yao
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy