Results 41 to 50 of about 331,521 (282)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Spatial ordering of primary defects at elevated temperatures [PDF]
We consider the microstructure evolution of a nonequilibrium system of primary defects, in which mobile point defects, vacancy loops, and sessile interstitial clusters are continuously produced by cascade-damage irradiation.
A. A. Semenov +3 more
core +1 more source
HeH+ under Spatial Confinement
In the present study, the influence of spatial confinement on the bond length as well as dipole moment, polarizability and (hyper)polarizabilities of HeH+ ion was analyzed.
Chołuj, Marta +5 more
core +1 more source
MULTI-CRITERIA GIS ANALYSES WITH THE USE OF UAVS FOR THE NEEDS OF SPATIAL PLANNING [PDF]
Utilization of Unmanned Aerial Systems (UAVs) in agriculture, forestry, or other environmental contexts has recently become common. However, in the case of spatial planning, the role of UAVs still seems to be underestimated.
D. Zawieska +7 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
POLA PEMANFAATAN DALAM TATA SPASIAL HUNIAN SUKU BAJO YANG BERKEMBANG DI KAMPUNG WURING KOTA MAUMERE
ABSTRAK. Tujuan penelitian ini untuk mengkaji pola pemanfaatan ruang dalam tata spasial hunian yang berkembang berupa sistem spasial hunian dan aspek-aspek yang melandasi pembentukan dan pemanfaatan spasial hunian Suku Bajo pada kawasan kampung Wuring ...
Ambrosius A.K.S. Gobang +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Retail spatial organisation and the physical city: bridging retail geography and urban morphology
The spatial organization of stores plays a crucial role in the production and development of the urban form while, at the same time, being strongly influenced from the physical constraints of the latter. Yet the connection between retail distribution and
Alessandro Araldi +2 more
doaj +1 more source
For subpixel mapping (SPM), ensuring the operational efficiency of the algorithm and mitigating the effect of abundance errors often cannot be achieved simultaneously.
Yujia Chen +9 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

