Results 71 to 80 of about 331,521 (282)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Nyeri County Spatial Plan 2020-2030

open access: yes, 2021
The Fourth Schedule of the Constitution of Kenya confers the role of County planning to the County Governments. Additionally, the County Government Act of 2012 requires each County Government to prepare a ten-year GISbased County Spatial Plan (CSP) in ...

core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Total-internal-reflection-fluorescence microscopy for the study of nanobubble dynamics

open access: yes, 2012
Nanobubbles can be observed with optical microscopy using the total-internal-reflection-fluorescence excitation. We report on total-internal-reflection-fluorescence visualization using rhodamine 6G at 5  μM concentration which results in strongly ...
Chan, Chon U., Ohl, Claus-Dieter
core   +1 more source

An overview of the research on the correlation between solar energy utilization potential and spatial morphology

open access: yesResults in Engineering
The combination of solar energy utilization and spatial morphology is crucial to improve urban energy efficiency. This paper explores the internal relationship between solar energy potential assessment and spatial form indicators from three aspects ...
Dexin Li   +3 more
doaj   +1 more source

Spatially Resolved Physical Properties of Young Star Clusters and Star-forming Clumps in the Brightest z>6 Galaxy, the Strongly Lensed Cosmic Spear at z=6.2

open access: yes
27 pages, 13 figures, submitted to ...
Abdurro'uf   +51 more
openaire   +2 more sources

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Urban development and the socio-spatial transformation of retail areas : a case study of provincial towns in Thailand [PDF]

open access: yes
This research aims to address the impact of globalisation on urban development process in the context of global South, through the case study of the socio-spatial dimensions of retail areas in three provincial Thai towns over the last 50 years ...
Santad, Chulawadee
core  

Langevin Dynamics with Spatial Correlations as a Model for Electron-Phonon Coupling

open access: yes, 2018
Stochastic Langevin dynamics has been traditionally used as a tool to describe nonequilibrium processes. When utilized in systems with collective modes, traditional Langevin dynamics relaxes all modes indiscriminately, regardless of their wavelength.
Samolyuk, G.,   +11 more
core   +1 more source

Magnetic noise from metal objects near qubit arrays

open access: yes, 2021
All metal objects support fluctuating currents that are responsible for evanescent-wave Johnson noise in their vicinity due both to thermal and quantum effects. The noise fields can decohere qubits in their neighborhood.
Kenny, Jonathan   +2 more
core   +1 more source

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