Results 201 to 210 of about 6,108,051 (246)

Tezepelumab in Chinese Patients With Severe Chronic Rhinosinusitis With Nasal Polyps: A Prespecified Subgroup Analysis of the Phase 3 WAYPOINT Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) in Chinese patients often exhibits a mixed Type 1/2/3 inflammatory phenotype (63%), potentially impacting the efficacy of biologics targeting Type 2 inflammation. This prespecified subgroup analysis of WAYPOINT (NCT04851964) evaluated the efficacy and safety of tezepelumab in Chinese
Li Hu, Houyong Li, Xicai Sun, Quan Liu, Yu Xu, Jiangang Fan, Andrew Foster, Claudia Chen, Yun Chon, Dehui Wang   +9 more
wiley   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

"I remember most of my family seeing it": The presence of others during child physical abuse, as conveyed in forensic interviews with Israeli children. [PDF]

Fam Process
Klebanov B, Katz C.
europepmc   +1 more source

Maternal, prenatal and postnatal risk factors for early child physical abuse: a French nationwide cohort study. [PDF]

Lancet Reg Health Eur
Blangis F, Drouin J, Launay E, Miranda S, Zureik M, Cohen JF, Weill A, Dray-Spira R, Chalumeau M.   +8 more
europepmc   +1 more source

Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy

Angewandte Chemie International Edition, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Physical and sexual abuse in women with functional constipation

The Turkish Journal of Gastroenterology, 1998
Ulus Salih AKARCA, Yüksek Hemşire Nimet TÜZOMAY, Eren AKÇİÇEK, Galip ERSÖZ, Ahmet AYDIN, Ömer ÖZÜTEMİZ, G. SEYLAN   +6 more
doaj  

The Role of Alexithymia and Moral Disengagement in Childhood Physical Abuse and Depressive Symptoms: A Comparative Study Among Rural and Urban Chinese College Students. [PDF]

Psychol Res Behav Manag
Lu X, Li Z, Zhu X, Li D, Wei J.
europepmc   +1 more source

Synthesis of Aminocyclopropanes by Redox‐Neutral Aminoalkylation

Angewandte Chemie International Edition, EarlyView.
Aminocyclopropane synthesis by hydroaminoalkylation utilizing cheap, readily available starting materials is presented, offering orthogonality to commonly used methods and allowing broad functional‐group tolerance. Solvent‐mediated conditions enable the reaction of a pre‐formed hemiaminal with alkenes and alkynes.
Gwyndaf A. Oliver, Konstantin Günther, Chiara Sebastianelli‐Schoditsch, Sophie Woolford, Iina Ludwig, Harald H. Sitte, Nuno Maulide   +6 more
wiley   +1 more source

Effectiveness of low dose computed tomography to detect fractures in paediatric suspected physical abuse: a systematic review. [PDF]

Int J Legal Med
Doyle E, Bugeja L, Dimmock MR, Lee KL, Ng J, Bassed RB.   +5 more
europepmc   +1 more source