Results 71 to 80 of about 6,108,051 (246)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Discovering Early‐Stage Gas Generation Kinetics Enables Thermal Runaway Early Warning in Lithium‐Ion Batteries

Advanced Science, EarlyView.
Operando gas diagnostics reveal a previously unrecognized chemical activation (CA) stage during thermal runaway in lithium‐ion batteries. A physics‐informed gas generation kinetics network (GGKNet) is developed to reconstruct reaction pathways and physical models automatically.
Jiabo Zhang, Qianzhen Guo, Shuaiqi Liu, Shuai Li, Xianghao Kong, Dong Han, Zhen Huang   +6 more
wiley   +1 more source

Spirit & Solace: Black Churches and Domestic Abuse Final Report [PDF]

, 2023
Background: The Spirit and Solace research wanted to find out what it is like for congregants in Black majority churches (BMCs) who report domestic abuse and their experiences of supporting fellow members.
Kanyeredzi, A, Wilson, J
core  

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

The impact of childhood abuse on patients with obsessive–compulsive disorder: an Egyptian study

Middle East Current Psychiatry
Background The presence of childhood abuse is expected to have a great impact on several psychological domains on obsessive–compulsive disorder (OCD) patients.
Yasser Abo Raya, Mohammad Gamal Sehlo, Reehab Saeed Mahdy, Heba Mesbah Kotb, Abdallah Saad Ibrahim   +4 more
doaj   +1 more source

Spontaneous Fractures or Physical Abuse?

Journal of Orthopedic and Spine Trauma, 2016
Spontaneous fractures occur in patients with Paget disease, Multiple myelomas, and osseous metastasis. Furthermore, spontaneous fractures may be the result of physiological pressure and stress on bones with reduced elastic tenacity.
Gholam Hossein Kazemian, Alireza Manafi Rasi, Farzad Amoozadeh Omrani, A Yamrali   +3 more
doaj   +1 more source

Commission to Eliminate Child Abuse and Neglect Fatalities [website]

, 2016
This website describes the history and activities of the Commission to Eliminate Child Abuse and Neglect Fatalities, established in 2012 by legislative mandate. It includes documentation and a final report that addresses the Commission's recommendations
United States. Commission to Eliminate Child Abuse and Neglect Fatalities.
core  

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Associations of emotional, physical and sexual abuse with network centrality in a population of Latina seasonal farmworkers

BMC Public Health
Background This study described exposure to abuse (emotional, sexual, and physical) against Latinas in the seasonal farmworker community, and visualized associations of exposure at three time points (past-month, past-12 months, and lifetime) with social ...
Lucy Sanchez, Juan G. Arroyo-Flores, Ariana L. Johnson, Tatiana Perrino, Lunthita M. Duthely, Edda Rodriguez, Mariano Kanamori   +6 more
doaj   +1 more source

A Descriptive study of child abuse cases in the paediatric emergency department (tertiary care hospital in Karachi)

Saudi Journal of Emergency Medicine
Background: Child abuse is an alarming issue that leads to lifelong health consequences, both physically and psychologically. The past few years, an increased number of abuse cases (sexual and physical) were reported in paediatric emergency departments ...
Hareem Ayub
doaj   +1 more source