Results 61 to 70 of about 1,066,636 (279)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improvement of the methodology for studying the physico-mechanical properties of thermoplastics soles

open access: yesVestnik of Vitebsk State Technological University
Today’s regulatory documents for the study of the physical and mechanical properties of materials for the bottom of shoes and molded soles are based on conducting tests using plates of materials of a certain thickness, within 1–3 mm (GOST 270-75 "Rubber.
Maria А. Neufeld, Alexander N. Burkin
doaj   +1 more source

Study of the effects of ethylene oxide-freon 12 upon properties of polymers and metallic surfaces Final report, 10 Oct. 1964 - 31 Mar. 1966 [PDF]

open access: yes
Physical, mechanical, and electrical tests to determine the effects on polymeric products after exposure to ethylene oxide-Freon ...
Landis, A. L., Rydelek, R. F.
core   +1 more source

Manufacturing of Composites by Pressure Infiltration, Structure and Mechanical Properties [PDF]

open access: yes, 2008
This paper presents the possibility of composite block production by using pressure infiltration technology. This method uses the pressure of an inert gas (usually argon or nitrogen) to force the melted matrix material to infiltrate the reinforcing ...
Dobránszky, János   +2 more
core  

Multi-Sample Thermobalance for Rapid Cyclic Oxidation Under Controlled Atmosphere [PDF]

open access: yes, 2004
When testing the resistance to oxidation of high temperature materials, the cyclic oxidation test is used as a reference because it integrates isothermal oxidation kinetics, oxide scale adherence, mechanical stresses, metallic alloy and oxide mechanical ...
Monceau, Daniel, Salabura, Jean-Claude
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Mechanical Properties and Microscopic Mechanisms of Expansive Soil under the Action of Acid and Alkali Solutions [PDF]

open access: yes长江科学院院报
[Objective] The aim of this study is to investigate the effects of acid-base conditions on the mechanical properties of expansive soil. [Methods] Expansive soil from Section C003 of the Yangtze-to-Huaihe Water Diversion Project was taken as the research ...
HU Bo, LI Wei, MA Kun, YUAN Rui-xiang, WANG Shuai, SUN Hui
doaj   +1 more source

Study and production of polybenzimidazole billets, laminates, and cylinders [PDF]

open access: yes
Mechanical properties and physical, chemical, and thermal tests of polybenzimidazole and carbon fabric laminates for spacecraft thermal ...
Marks, B. S.   +2 more
core   +1 more source

Modeling of properties of fiber reinforced cement composites [PDF]

open access: yes, 2008
This paper presents the results of authors' laboratory testing of the influence of steel fibers as fiber reinforcement on the change of properties of cement composite mortar and concrete type materials.
Jevtić Dragica   +2 more
core   +1 more source

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