Results 121 to 130 of about 2,670,212 (192)

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

open access: yesAdvanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi   +13 more
wiley   +1 more source

Two SOX11 variants cause Coffin–Siris syndrome with a new feature of sensorineural hearing loss

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 183-189, January 2023., 2023
Abstract Coffin‐Siris syndrome (CSS, OMIM#135900) is a rare congenital disorder associated with neurodevelopmental and dysmorphic features. The primary cause of CSS is pathogenic variants in any of 9 BAF chromatin‐remodeling complex encoding genes or the genes SOX11 and PHF6. Herein, we performed whole‐exome sequencing (WES) and a series of analyses of
Qiuquan Wang   +5 more
wiley   +1 more source

Musculoskeletal ultrasonography in physical and rehabilitation medicine

open access: gold, 2012
Levent Özçakar   +3 more
openalex   +1 more source

Assessing Competency in Physical Medicine and Rehabilitation Residency: the ACGME Milestones Initiative [PDF]

open access: bronze, 2015
Julian Willoughby   +2 more
openalex   +1 more source

Chronic, Battery‐Free, Fully Implantable Multimodal Spinal Cord Stimulator for Pain Modulation in Small Animal Models

open access: yesAdvanced Science, EarlyView.
This work introduces wireless‐powered fully implantable spinal cord stimulation (SCS) in freely moving animal models, supporting diverse ethological paradigms. kHz stimulation with real‐time digital programming offers versatile, dynamically optimized therapy. Scalable fabrication ensures high N studies and seamless translation.
Allie J. Widman   +11 more
wiley   +1 more source

Physical and Rehabilitation Medicine (PRM) care pathways: “Patients after total hip arthroplasty”

open access: bronze, 2012
P. Ribinik   +7 more
openalex   +1 more source

Viridicatol from the Deep‐Sea‐Derived Fungus Alleviates Bone Loss by Targeting the Wnt/SHN3 Pathway

open access: yesAdvanced Science, EarlyView.
Viridicatol (VDC), isolated from the deep‐sea‐derived fungus, enhances osteogenesis in vitro and in vivo by targeting Wnt/SHN3 signaling pathway. It can be delivered via engineered nanovesicles to mitigate bone loss of osteoporosis, fracture repair, and osteogenesis imperfecta.
Chun‐Lan Xie   +10 more
wiley   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang   +10 more
wiley   +1 more source

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