Results 91 to 100 of about 8,035,377 (307)

Carotid stiffness and physical activity in elderly : a short report of the SAPALDIA 3 cohort study [PDF]

open access: yes, 2015
Regular physical activity has been shown to reduce cardiovascular disease risk in the general population. While smaller studies in specified groups (highly trained versus untrained individuals) indicate a certain dose-dependent effect of physical ...
Wanner, Miriam   +27 more
core   +2 more sources

Microbiology and atmospheric processes: Biological, physical and chemical characterization of aerosol particles [PDF]

open access: yes, 2008
The interest in bioaerosols has traditionally been linked to health hazards for humans, animals and plants. However, several components of bioaerosols exhibit physical properties of great significance for cloud processes, such as ice nucleation and cloud
R. Psenner   +18 more
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Distinct magneto-Raman signatures of spin-flip phase transitions in CrI3

open access: yesNature Communications, 2020
Thin samples CrI3 exhibit a phase transition under an applied magnetic field from layered antiferromagnetism to ferromagnetism. Here the authors observe an associated abrupt change in the magneto-Raman spectra, illustrating the sensitivity of Raman ...
Amber McCreary   +18 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A critical challenge: Developing student's critical abilities [PDF]

open access: yes, 2014
The work of educators includes grappling with the challenges of bringing theoretical concepts and approaches into day-to-day physical education practice for quality programmes and the betterment of student learning. One of our most exciting challenges is
McBain, Sue, Gillespie, Lorna B.
core  

Optimization of Solid Lipid Nanoparticle Formulation Using Design of Experiments, PART I: Strategic Tool for the Determination of Critical Parameters Regarding Formulation and Process

open access: yesNanomaterials
This study presents a methodological framework for optimizing “blank” solid lipid nanoparticles (SLNs), focusing on the use of a design of experiments (DOE) approach.
Margot Cassayre   +5 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Environmental monitoring and characterization /

open access: yes, 2004
Environmental Monitoring and Characterization is an integrated, hands-on resource for monitoring all aspects of the environment. Sample collection methods and relevant physical, chemical and biological processes necessary to characterize the environment ...
Artiola, Janick F.   +2 more
core  

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