Results 141 to 150 of about 8,160,201 (307)

Physical Chemistry of Chloroquine Permeation through the Cell Membrane with Atomistic Detail. [PDF]

open access: yesJ Chem Inf Model, 2023
Paulikat M   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Probabilistic Physico-Chemical Diffusion Model of the Key Drifting Parameter of Measuring Equipment

open access: yesAxioms
(1) Background: A new probabilistic physico-chemical model of the drifting key parameter of measuring equipment is proposed. The model allows for the integrated consideration of degradation processes (electrolytic corrosion, oxidation, plastic ...
Rustam Khayrullin
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Reduced protein solubility – cause or consequence in amyloid disease?

open access: yesQRB Discovery
In this perspective, we ask the question whether the apparently lower solubility of specific proteins in amyloid disease is a cause or consequence of the protein deposition seen in such diseases. We focus on Alzheimer’s disease and start by reviewing the
Max Lindberg   +3 more
doaj   +1 more source

Physical Chemistry Study of Collagen-Based Multilayer Films. [PDF]

open access: yesGels, 2023
Chen YW   +4 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy