Results 71 to 80 of about 65,391 (307)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Assessment of bed clogging in surface water reservoirs under different hydrologic conditions
Ain Shams Engineering JournalPhysical clogging of porous media plays an important role in controlling their hydraulic conductivity. This study investigates how uniformly graded medium-to-coarse sand in a reservoir’s bed performs in response to the inflow of turbid water with fine ...
Ahmed N. Abdel-Azim +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
e-Journal of Nondestructive Testing, 2023 Eddy current testing (ECT) of Steam Generator (SG) tubes is part of the maintenance program of Nuclear Power Plants. Tube Support Plates (TSP) are usually only considered as extraneous signals for tube inspection. However, for long-term operation of SGs,
Audrey Vigneron +3 more
doaj +1 more source
Freeform Extrusion of High Solids Loading Ceramic Slurries, Part I: Extrusion Process Modeling [PDF]
, 2006 A novel solid freeform fabrication method has been developed for the manufacture of ceramic-based components in an environmentally friendly fashion. The method is based on the extrusion of ceramic slurries using water as the binding media.
Hilmas, Gregory E. +4 more
core +2 more sources
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Role of micro-nanobubble water aeration on emitter clogging and uniformity of drip irrigation system
Agricultural Water ManagementDrip irrigation system (DIS) is widely adopted around the world. Whereas the surge in global food demand has heightened the dire increase in technological advancements in conventional DIS.
Abdul Rahim Junejo +4 more
doaj +1 more source
Spontaneous Jamming in One-Dimensional Systems
, 1997 We study the phenomenon of jamming in driven diffusive systems. We introduce a simple microscopic model in which jamming of a conserved driven species is mediated by the presence of a non-conserved quantity, causing an effective long range interaction of
+18 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source