Results 31 to 40 of about 1,360,407 (261)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

A Bayesian approach to estimate minute ventilation from heart rate during exercise for assessing environmental exposures of females

Physiological Reports
Estimating minute ventilation (V̇E) is essential for assessing the health impacts of environmental exposures during exercise field‐studies. Predictive equations using heart rate (HR) are commonly used, but overlook exercise intensity domains, and reduced
Gustavo Oneda, Fernando Klitzke Borszcz, Raul Würdig, Ricardo Dantas deLucas, Rosemeri Maurici, Joseph F. Welch, Sarah Koch, Ramon Cruz   +7 more
doaj   +1 more source

Unlocking superior mechanical properties: the synergistic enhancement of hardness and fracture toughness in nanopolycrystalline tantalum diboride

Advanced Powder Materials
Achieving optimal mechanical properties, including hardness and fracture toughness, by controlling grain size is a fundamental and long-standing objective in the development of hard and superhard transition metal borides (TMBs) ceramics.
Shuailing Ma, Yufei Ge, Min Lian, Xiao Ma, Pinwen Zhu, Akhil Tayal, Xingbin Zhao, Wei Li, Hao Song, Zihan Zhang, Yunxian Liu, Xiaobing Liu, Tian Cui   +12 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Review Articles on Soccer Performance Analysis: A Bibliometric Analysis of Current Trends and Emerging Themes

Sports
Objectives: This study aimed to analyze review articles on soccer performance analysis (PA) using a bibliometric approach to address three main research questions: (a) How has the publication of review articles related to soccer PA evolved over time? (b)
Spyridon Plakias
doaj   +1 more source

Suicidality and Its Relation with Physical and Mental Conditions: Results from a Cross-Sectional Study of the Nationwide Primary Care Population Sample in Latvia

Medicina, 2021
Background and Objectives: Physical and mental conditions are important risk factors for suicidality. However, there is no clear understanding of these relationships and the effect of co-occurrence on suicidality. We aimed to investigate the associations
Lubova Renemane, Anda Kivite-Urtane, Elmars Rancans   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Stabilization of High‐Pressure Phase of Face‐Centered Cubic Lutetium Trihydride at Ambient Conditions

Advanced Science
Superconductivity at room temperature and near‐ambient pressures is a highly sought‐after phenomenon in physics and materials science. A recent study reported the presence of this phenomenon in N‐doped lutetium hydride [Nature 615, 244 (2023)], however ...
Xin Li, Ying Wang, Yuhao Fu, Simon A. T. Redfern, Shuqing Jiang, Pinwen Zhu, Tian Cui   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source