Results 41 to 50 of about 7,176,228 (272)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Animal Flow as a Supplementary Training Tool for Basketball: A 12-Week Randomized Controlled Trial
Pamukkale Spor Bilimleri DergisiThis study aimed to evaluate the effects of integrating Animal Flow into traditional basketball training on physical performance in university athletes, focusing on agility, core endurance, proprioceptive awareness, repeated sprint ability, flexibility ...
Buğra Çağatay Savaş +9 more
doaj +1 more source
Annali dell'Istituto Superiore di Sanità, 2014 An epistemological foundation for cultural psychology is essential to neuro- and behavioural sciences for the challenge psychological sciences must currently face: searching for an explanation of how a brain can become a mind and how individuals assign a
Adele De Pascale
doaj +1 more source
Techne, 2020 «Sun does not always shine and the wind does not always blow» (Rifkin, 2011). Looks like we have a problem. Our problem is time. It is an ancient human problem to want to predict.
Teodoro Georgiadis
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An Operant Conditioning Task to Assess the Choice between Wheel Running and Palatable Food in Mice
Bio-Protocol, 2019 Wheel running, especially in the homecage, has been widely used to study the neurobiology of exercise because animal tends to use it voluntarily.
Bastien Redon +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Impact of enriched environment on motor performance and learning in mice
Scientific ReportsNeuroscience heavily relies on animal welfare in laboratory rodents as it can significantly affect brain development, cognitive function and memory formation.
S. Dijkhuizen +5 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source