Results 101 to 110 of about 6,242,189 (313)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Physical Conditioning & Fatigue (30)

, 1969
Physical Conditioning & Fatigue: Exercise Record for P ...

core  

Physical Conditioning Strategies for the Prevention of Concussion in Sport: a Scoping Review. [PDF]

Sports Med Open, 2021
Garnett D, Patricios J, Cobbing S.
europepmc   +1 more source

Neuroimmune braking mechanisms in exercise-related musculoskeletal injury: from nociceptors to tissue regeneration

Journal of Neuroinflammation
Background Musculoskeletal injuries are a frequent occurrence in sports medicine and rehabilitation, and their healing process needs an accurate response from inflammation.
Enli Xie, Yushan He, Tainan Cao, Changchun Li, Zhiming Wang   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Physical Conditioning & Fatigue (23)

, 1970
Physical Conditioning & Fatigue: Exercise record for J ...

core  

Soldier Load Carriage, Injuries, Rehabilitation and Physical Conditioning: An International Approach. [PDF]

Int J Environ Res Public Health, 2021
Orr R, Pope R, Lopes TJA, Leyk D, Blacker S, Bustillo-Aguirre BS, Knapik JJ.   +6 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Heating, ventilating, air-conditioning guide.

Vols. for 1922-37 issued as Guide of the American Society of Heating and Air-Conditioning Engineers under its earlier name.Vols. for 1922-59 published by the American Society of Heating and Air-Conditioning Engineers (called 1922-54, American Society of ...
American Society of Heating, Refrigerating and Air-Conditioning Engineers, American Society of Heating and Air-Conditioning Engineers. Guide., American Society of Heating and Air-Conditioning Engineers   +2 more
core  

Physical Conditioning & Fatigue (24)

, 1970
Physical Conditioning & Fatigue: Exercise record for J ...

core