Results 71 to 80 of about 5,816,940 (303)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Physical Conditioning & Fatigue (26)

, 1970
Physical Conditioning & Fatigue: Exercise record for J ...

core  

Analysis of kinematic factors influencing performance in the Chinese men’s 4 × 100 m relay team

Scientific Reports
To investigate the key factors influencing performance in the men’s 4 × 100 m relay, this study analyzed the relationship between baton exchange kinematics and relay zone performance.
Zhao Li, Caizheng Yue, Zhen Li, Xicheng Wang, Haokai Xu, Zhongshuo Zhao, Keli Deng   +6 more
doaj   +1 more source

Effects of Mind–Body Exercise on Bone Health in Perimenopausal Women: A Systematic Review and Three-Level Meta-Analysis

Life
The perimenopausal phase represents a critical window for early intervention against accelerated bone loss, highlighting an urgent need for safe and accessible non-pharmacological strategies.
Zhuo Zeng, Chengyu Zhou, Lin Luo, Shuaihao Zhao, Xusong Dong, Wenhui Yin, Wenyan Yin, Dongxu Huang, Haoqiang Shi, Haoran Li, Yongmin Xie, Aiguo Zhou, Chengyi Zhang   +12 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Physical Conditioning & Fatigue (33)

, 1969
Physical Conditioning & Fatigue: Exercise record for J ...

core  

Effects of multi-ingredient protein supplementation combined with exercise intervention on body composition and muscle fitness in healthy women: a systematic review with multilevel meta-analysis

Frontiers in Nutrition
ObjectivesThis meta-analysis investigated whether multi-ingredient protein supplements (MIPS) combined with exercise improve body composition and muscle fitness in women.
Chengyu Zhou, Muen Qiu, Zhuo Zeng, Qi Xie, Kai Xu, Kai Xu, Henghao Yan, Bo Wang, Bopeng Qiu, Guoxin Shi   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Physical Conditioning & Fatigue (21)

, 1970
Physical Conditioning & Fatigue: Exercise Record for Subject J ...

core  

Acute caffeine supplementation in rugby players: a systematic review and meta-analysis of physical performance, sport-specific performance, perceptual responses, and physiological markers

Frontiers in Nutrition
BackgroundRugby is a collision-based team sport requiring repeated high-intensity sprinting, technical execution, and physical contact under fatigue. Although caffeine is used as an ergogenic supplement, evidence from mixed team-sport populations may not
Jun Li, Dawei Zhou, Tianle Wang, Zeyong Liu, Zhuo Zeng, Caizheng Yue, Cong Huang, Weixin Chen, Junyi Shu, Fanhao Meng   +9 more
doaj   +1 more source