Results 51 to 60 of about 6,242,189 (313)

Pilates Method as a complementary activity reduces myofascial stiffness and pain in women with breast cancer undergoing aromatase inhibitor therapy: a randomized controlled trial

Scientific Reports
Evidence supporting the effectiveness of non-pharmacological exercise interventions to mitigate the side effects of aromatase inhibitor (AI) therapy among breast cancer (BC) patients remains limited.
Maria Tarnas, Rafał Stemplewski, Monika Ciekot-Sołtysiak, Barbara Pospieszna, Joanna Kufel-Grabowska, Andrzej Marszałek, Jacek Zieliński, Ewa Ziemann   +7 more
doaj   +1 more source

Effect of Power Output and Pedaling Cadence on Plantar Pressures in Professional Cyclists with Overuse Injuries

Sports
Background: Plantar pressure analysis provides insight into load distribution at the foot–pedal interface during cycling; however, its modulation by pedaling power, cadence, and overuse injury status remains poorly understood by professional cyclists. It
Dídac Navarro-Martínez, Javier Zahonero, Pablo Vera, José Martí-Martí, Florentino Huertas, Carlos Barrios   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Effects of variable resistance training with different load ratios on lower-limb strength and power in male college students

Journal of Exercise Science & Fitness
Objective: The optimum relationship combination of variable to constant resistance within variable resistance training (VRT) for enhancing lower-limb strength and power remains unclear.
Changbo Pan, Wei Li, Yuying Su, Yu Shi
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Development of an International Qualification Framework for the strength and conditioning profession: International Universities Strength and Conditioning Association Position Statement.

In the profession of strength and conditioning (S&C), there is a need for a standardised, comprehensive framework that can allow for the alignment of international certifications, qualifications, and standards.
Bird, Stephen P., Langford, Andrew, Flannagan, Aden, Marchetti, Paulo H.   +3 more
core   +1 more source

A 24-week multi-component exercise program improves cognition and body composition in older adults with mild cognitive impairment: a randomized controlled trial

Frontiers in Aging Neuroscience
BackgroundThis study investigated whether a 24-week, community-based multicomponent exercise intervention (MCEI) can improve body composition and cognitive function in older adults with mild cognitive impairment (MCI).MethodsIn this single-center ...
Danming Xu, Xiaochu Wu, Junming Dai, Qing Li, Zhi Wang, Yimin Huang, Yu Zhang, Junjie Cao, Bingxue Li, Yirong Dong, Yanhao Tu   +10 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Kinetic analysis of change of direction simulating a defensive action in soccer players with and without acute fatigue

Heliyon
The objective of this study is to analyse the kinetic effects of acute fatigue during a 45° change of direction executed with the non-dominant limb, emulating a typical defensive action during pressing in soccer.
Matías de Pablo, Carol Torres, David Ulloa-Díaz, Gabriel Fábrica   +3 more
doaj   +1 more source

Subjective assessment and biochemical evaluation of traction therapy in women with chronic low back pain: does body mass index matter? A clinical study

BMC Musculoskeletal Disorders, 2023
Background Apart from the positive effect of lumbar traction on structural changes within the spine in patients with low back pain, it is likely that therapeutic effects are correlated with pain biomarkers in the blood.
Marzena Ratajczak, Michał Wendt, Ewa Śliwicka, Damian Skrypnik, Jacek Zieliński, Krzysztof Kusy, Piotr Krutki, Małgorzata Waszak   +7 more
doaj   +1 more source