Results 51 to 60 of about 5,816,940 (303)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Effects of variable resistance training with different load ratios on lower-limb strength and power in male college students

Journal of Exercise Science & Fitness
Objective: The optimum relationship combination of variable to constant resistance within variable resistance training (VRT) for enhancing lower-limb strength and power remains unclear.
Changbo Pan, Wei Li, Yuying Su, Yu Shi
doaj   +1 more source

Subjective assessment and biochemical evaluation of traction therapy in women with chronic low back pain: does body mass index matter? A clinical study

BMC Musculoskeletal Disorders, 2023
Background Apart from the positive effect of lumbar traction on structural changes within the spine in patients with low back pain, it is likely that therapeutic effects are correlated with pain biomarkers in the blood.
Marzena Ratajczak, Michał Wendt, Ewa Śliwicka, Damian Skrypnik, Jacek Zieliński, Krzysztof Kusy, Piotr Krutki, Małgorzata Waszak   +7 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A 24-week multi-component exercise program improves cognition and body composition in older adults with mild cognitive impairment: a randomized controlled trial

Frontiers in Aging Neuroscience
BackgroundThis study investigated whether a 24-week, community-based multicomponent exercise intervention (MCEI) can improve body composition and cognitive function in older adults with mild cognitive impairment (MCI).MethodsIn this single-center ...
Danming Xu, Xiaochu Wu, Junming Dai, Qing Li, Zhi Wang, Yimin Huang, Yu Zhang, Junjie Cao, Bingxue Li, Yirong Dong, Yanhao Tu   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Kinetic analysis of change of direction simulating a defensive action in soccer players with and without acute fatigue

Heliyon
The objective of this study is to analyse the kinetic effects of acute fatigue during a 45° change of direction executed with the non-dominant limb, emulating a typical defensive action during pressing in soccer.
Matías de Pablo, Carol Torres, David Ulloa-Díaz, Gabriel Fábrica   +3 more
doaj   +1 more source

Effects of physical activity distribution patterns on basketball skill acquisition and physical exercise self-efficacy among Chinese male university students: a randomised controlled trial [PDF]

PeerJ
Background As an open-skills sport, basketball not only enhances university students’ physical fitness and specialised techniques but also influences their technical learning efficiency and exercise self-efficacy through patterns of physical activity ...
Zhuoxiao Liu, Chengyu Zhou, Zhuo Zeng, Huaibo Yang   +3 more
doaj   +2 more sources

Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial

Nutrition & Metabolism, 2023
Background Higher circulating levels of trimethylamine N-oxide (TMAO), which is a metabolite that can be produced by the gut microbiota from L-carnitine (LC), have been associated with bone mineral density (BMD).
Robert A. Olek, Emilia Samborowska, Piotr Wisniewski, Pawel Wojtkiewicz, Krystian Wochna, Jacek Zielinski   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source