Results 41 to 50 of about 2,161,742 (288)
ETHNOPEDAGOGICAL COMPONENT OF PHYSICAL TRAINING OF SCHOOLCHILDREN
Introduction. The publication is devoted to the problem of the use of ethnopedagogical technologies in physical training of school students.The aim of the research is to describe a new approach to the organization of physical education of school students
M. M. Kolokoltsev
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Optimal Locating for Physical Development of Sorkhankalate City, Using Analytic Hierarchy Process Method )AHP) [PDF]
Today, one of the most important and complex issues for urban programmers and decision making is locating suitable places for future development of cities and determining suitable lands, which this objective will obtain with a comprehensive view on ...
Ahmad PurAhmad +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Construction of somatic and motor skills of students in adolescence. [PDF]
This study attempts to discuss issues concerning determinants of somatic and motor development of young people from the VII High School name Wanda Szuman in Torun.
Napierala Marek. +3 more
doaj
Spatial analysis of Environmental Suitability of Shiraz City Using Environmental Suitability Analysis [PDF]
Urban Physical development has been the major concern of urban planners during recent years, therefore, better understanding of urban and its development is necessary for sustainable development.
Dr.Mohammadreza Rezaei +2 more
doaj +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

