Results 81 to 90 of about 575 (106)
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Journal of Neuroscience Methods, 2021
In the neurosciences, the physical disector method represents an established quantitative stereological method for unbiased sampling and counting of cells in histological tissue sections of known thickness. Physical disector analyses are conventionally performed using plastic-embedded tissue samples, because plastic-embedding causes a comparably low ...
Isabel Hofmann +2 more
exaly +3 more sources
In the neurosciences, the physical disector method represents an established quantitative stereological method for unbiased sampling and counting of cells in histological tissue sections of known thickness. Physical disector analyses are conventionally performed using plastic-embedded tissue samples, because plastic-embedding causes a comparably low ...
Isabel Hofmann +2 more
exaly +3 more sources
Journal of Microscopy, 1993
SummaryA simple modification of the physical disector is presented, which is used to count the number of neurons in the hypoglossal nucleus of the rat in a series of paraffin sections. One disector consists of two adjacent sections (6 μm thick) that have been Nissl‐stained with cresyl fast violet.
Orlando Guntinas-Lichius +2 more
exaly +3 more sources
SummaryA simple modification of the physical disector is presented, which is used to count the number of neurons in the hypoglossal nucleus of the rat in a series of paraffin sections. One disector consists of two adjacent sections (6 μm thick) that have been Nissl‐stained with cresyl fast violet.
Orlando Guntinas-Lichius +2 more
exaly +3 more sources
Journal of Microscopy, 2000
A novel modification of the physical disector is described which was used to estimate the total number of terminal bronchiolar duct endings (TBDEs) in human infant lung. TBDEs are closed three‐dimensional space curves of complex shape that are inherently difficult to count from histological sections.
C V Howard, P D Sibbons, D Van Velzen
exaly +3 more sources
A novel modification of the physical disector is described which was used to estimate the total number of terminal bronchiolar duct endings (TBDEs) in human infant lung. TBDEs are closed three‐dimensional space curves of complex shape that are inherently difficult to count from histological sections.
C V Howard, P D Sibbons, D Van Velzen
exaly +3 more sources
The connEulor: Unbiased estimation of connectivity using physical disectors under projection
Bone, 1993The Euler number and the connectivity of an arbitrary object is defined, and it is illustrated why the connectivity of an n-dimensional object cannot be estimated in an (n-1)-dimensional section. The disector--principle for 3-D counting of the Euler--events is illustrated in cancellous bone.
Gundersen, H. J.G. +3 more
openaire +3 more sources
Journal of Chemical Neuroanatomy, 2018
A quantitative description of a three-dimensional (3D) object based on two-dimensional images can be made using stereological methods These methods involve unbiased approaches and provide reliable results with quantitative data. The quantitative morphology of the nervous system has been thoroughly researched in this context.
Kıymet Kübra Yurt +6 more
openaire +2 more sources
A quantitative description of a three-dimensional (3D) object based on two-dimensional images can be made using stereological methods These methods involve unbiased approaches and provide reliable results with quantitative data. The quantitative morphology of the nervous system has been thoroughly researched in this context.
Kıymet Kübra Yurt +6 more
openaire +2 more sources
Journal of Comparative Neurology, 2001
AbstractThe synapse, as the site of functional neural interaction, has been suggested as a possible substrate for age‐related impairment of cognitive ability. Using the physical disector probe with tissue prepared for ultrastructural analysis, we find an age‐related decline in the numerical density of presumptive inhibitory synapses in layer 2 of the ...
B H, Poe +2 more
openaire +2 more sources
AbstractThe synapse, as the site of functional neural interaction, has been suggested as a possible substrate for age‐related impairment of cognitive ability. Using the physical disector probe with tissue prepared for ultrastructural analysis, we find an age‐related decline in the numerical density of presumptive inhibitory synapses in layer 2 of the ...
B H, Poe +2 more
openaire +2 more sources
Anatomical Science International, 2005
Stereology is a group of mathematical and statistical methods that allows the extrapolation of three-dimensional structural information from two-dimensional sections (or slices). This allows researchers to derive important quantitative structural information, such as the volume, surface area or numbers of particular particles (e.g.
Miki, +8 more
openaire +3 more sources
Stereology is a group of mathematical and statistical methods that allows the extrapolation of three-dimensional structural information from two-dimensional sections (or slices). This allows researchers to derive important quantitative structural information, such as the volume, surface area or numbers of particular particles (e.g.
Miki, +8 more
openaire +3 more sources
2012
Design-based stereology is considered the gold-standard method for estimating the total number of glomeruli, and thereby nephrons, in the adult kidney. However, until recently, a design-based method for estimating nephron number in the developing kidney was not available.
Cullen-Mcewen, Luise A. +3 more
openaire +3 more sources
Design-based stereology is considered the gold-standard method for estimating the total number of glomeruli, and thereby nephrons, in the adult kidney. However, until recently, a design-based method for estimating nephron number in the developing kidney was not available.
Cullen-Mcewen, Luise A. +3 more
openaire +3 more sources
NeuroQuantology, 2012
Estimation of cerebellar Purkinje cell number is an important evaluation parameter for the study of the development of the cerebellum as well as for investigating the changes occurring in various experimental and physiological conditions. The introduction of stereological techniques in biological and biomedical research has made quantification of ...
Chintawar, Satyan +3 more
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Estimation of cerebellar Purkinje cell number is an important evaluation parameter for the study of the development of the cerebellum as well as for investigating the changes occurring in various experimental and physiological conditions. The introduction of stereological techniques in biological and biomedical research has made quantification of ...
Chintawar, Satyan +3 more
openaire +2 more sources
2012
Nephron number has emerged as a useful parameter for assessing the roles of specific genes and feto-maternal environmental factors in kidney development. Nephron number is also of clinical interest due to increasing evidence suggesting that low nephron number is associated with increased risk for developing chronic adult disease, including ...
Luise A, Cullen-McEwen +2 more
openaire +2 more sources
Nephron number has emerged as a useful parameter for assessing the roles of specific genes and feto-maternal environmental factors in kidney development. Nephron number is also of clinical interest due to increasing evidence suggesting that low nephron number is associated with increased risk for developing chronic adult disease, including ...
Luise A, Cullen-McEwen +2 more
openaire +2 more sources