Results 91 to 100 of about 283,703 (294)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Social processing distorts physical distance perception

Scientific Reports
Abstract Psychopathy is traditionally linked to higher-level cognitive processes, but its impact on low-level cognitive functions has remained largely unexplored. This study investigates the relationship between the fundamental cognitive function of physical distance estimation and our social predisposition towards others, as captured by ...
Georgios Michalareas, Claudia Lehr, Matthias Grabenhorst, Heiko Hecht   +3 more
openaire   +3 more sources

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Covid-19 Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing: a study protocol [version 1; peer review: 2 approved]

HRB Open Research, 2020
Introduction: Covid-19 was declared a pandemic in March 2020. Since then, governments have implemented unprecedented public health measures to contain the virus.
M. Isabela Troya, Ali Khashan, Patricia Kearney, Ella Arensman, Philipp Hoevel, Claire Buckley, Margaret Fitzgerald, Rory Humphries, Elizabeth Kiely, Kieran Mulchrone, Mike Murphy, Lois O'Connor, Joan O'Donnell, Eilis O’Reilly, Micheal O'Riordain, Mary Spillane, Sebastian Wieczorek, Ivan J Perry   +17 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Covid-19 Estimating the burden of symptomatic disease in the community and the impact of public health measures on physical, mental and social wellbeing: a study protocol [version 2; peer review: 2 approved]

HRB Open Research, 2020
Introduction: Covid-19 was declared a pandemic in March 2020. Since then, governments have implemented unprecedented public health measures to contain the virus.
M. Isabela Troya, Ali Khashan, Patricia Kearney, Ella Arensman, Philipp Hoevel, Claire Buckley, Margaret Fitzgerald, Rory Humphries, Elizabeth Kiely, Kieran Mulchrone, Mike Murphy, Lois O'Connor, Joan O'Donnell, Eilis O’Reilly, Micheal O'Riordain, Mary Spillane, Sebastian Wieczorek, Ivan J Perry   +17 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Planning for classroom physical distancing to minimize the threat of COVID-19 disease spread.

PLoS ONE, 2020
The coronavirus disease 2019 is a respiratory illness spread between people. A primary weapon for reducing or eliminating this disease involves physical distancing to thwart transmission.
Alan T Murray
doaj   +1 more source

Epidemics on Networks: Reducing Disease Transmission Using Health Emergency Declarations and Peer Communication

, 2019
Understanding individual decisions in a world where communications and information move instantly via cell phones and the internet, contributes to the development and implementation of policies aimed at stopping or ameliorating the spread of diseases. In
Azizi, Asma, Castillo-Chavez, Carlos, Espinoza, Baltazar, Kang, Yun, Montalvo, Cesar   +4 more
core   +1 more source

Management of Agitation During the COVID-19 Pandemic [PDF]

, 2020
The coronavirus disease 2019 (COVID-19) pandemic caused by the coronavirus SARS-CoV-2 has radically altered delivery of care in emergency settings.
Chang, Bernard P., Powsner, Seth, Roppolo, Lynn P., Rozel, John S., Wilson, Michael P., Wong, Ambrose H., Yonkers, Kimberly A.   +6 more
core