Results 51 to 60 of about 1,185,659 (239)

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Effects of exercise interventions on physical function, cognitive function and quality of life of frail older adults in nursing homes: a systematic review and meta-analysis

Frontiers in Psychology
ObjectiveOlder adults often face frailty as they age, characterized by a decline in physical and mental health, leading to increased reliance on caregiving services, particularly in nursing homes. Exercise interventions have emerged as an effective means
Yingbo Zhu, Yu Zhang, Xiao Li, Zhijuan Du   +3 more
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

Analysis of the significance and gender differences in the factors influencing antisocial behaviors among adolescents

Scientific Reports
Adolescent antisocial behavior not only has an adverse effect on the healthy development of adolescents but also poses a threat to social order and public safety.
Wenze Sui, Yan Gao, Liangyu Zhao, Yuke Yang, Lu Chen, Yining Hu, Xiangren Yi, Shuoqin Zhang, Sen Ma   +8 more
doaj   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Associations between meeting 24-hour movement guidelines and health-related quality of life in older adults: a systematic review and meta-analysis

BMC Public Health
Background Adherence to 24-h movement guidelines that include physical activity (PA), sedentary behaviour (SB), and sleep is linked to improved health outcomes, yet its impact on health-related quality of life (HRQoL) in older adults remains ...
Wei Tuo, Poyong Yan, Weijie Qin, Liang Li, Zhou Zhou, Tiantian Zhang, Lu Chen, Yagang Song, Aiwei Wang   +8 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Foot arch morphology and lower-limb biomechanical characteristics in university students: a cross-sectional multifactorial analysis of 1,078 participants

Scientific Reports
To examine how medial longitudinal arch morphology relates to a multidomain set of static biomechanical correlates—covering structure (forefoot/rearfoot alignment), loading/pressure behavior, arch “spring-like” function, and postural-control surrogates ...
Zhiyi Xu, Yu Lin, Yiquan Chen, Jie Lu, Yihui Jiang, Jiahao He, Liyuan Yu, Wensheng Miao, Jinhui Yan, Xiangdong Wang   +9 more
doaj   +1 more source

Effects of Resistance Exercise and Fermented Soybean Consumption on Glucose Tolerance and Expressions of Immune Senescence-Related Myokines in Middle-Aged Obese Rats

Journal of Obesity & Metabolic Syndrome, 2018
Background: It is important for older adults to prevent sarcopenia, but there are not currently effective methods to maintain or improve skeletal muscle function or immune function in this population.
Kijin Kim, Nayoung Ahn, Suryun Jung, Youngsik Ju, Gyuho Lee, Miyeon Kim, Yongjin Jeong   +6 more
doaj   +1 more source