Results 51 to 60 of about 4,874,678 (301)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Changes in somatic build, body composition and motor performance of young female volleyball players in the preparatory period for the season

Journal of Education, Health and Sport, 2018
Introduction. Volleyball is one of the most popular sports in Poland. In recent years, there is a growing interest in this discipline among young people.
Adrian Sieroń, Jadwiga Pietraszewska
doaj   +3 more sources

THE IMPLEMENTATION OF PHYSICAL EDUCATION IN DISABLE SCHOOL (SLB) AROUND CITY OF YOGYAKARTA INDONESIA [PDF]

, 2005
This study is aimed to find out the implementation of physical education in Disable School around City of Yogyakarta Indonesia. Specifically, the implementation of Physical Education according to the teacher's perception and the student's perception ...
Sumaryanto
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Effects of mini-basketball training program on social communication impairments and regional homogeneity of brain functions in preschool children with autism spectrum disorder

BMC Sports Science, Medicine and Rehabilitation
Background Social communication impairments (SCI) is a core symptom of autism spectrum disorder (ASD) and is marked by challenges in social interaction.
Yang Yang, Dandan Chen, Kelong Cai, Lina Zhu, Yifan Shi, Xiaoxiao Dong, Zhiyuan Sun, Zhiyuan Qiao, Yahui Yang, Weike Zhang, Haiyong Mao, Aiguo Chen   +11 more
doaj   +1 more source

‘Deliberate Preparation’ as an evidence-based focus for primary physical education [PDF]

There is substantial scientific research suggesting the physical and psychological health benefits of a physically active lifestyle. Consequently, governments worldwide prioritize policies, finances, and resources in healthcare, education, and sports ...
Aelterman N., Berry J., Bompa T. O., Bouffard M., Côte J., Goodway J. D., Horn T. S., Jess M., Sheehan D., Starkes J. L., Van Biljon A., Whitehead M.   +11 more
core   +1 more source

Newly qualified physical education teachers’ experiences of developing subject knowledge prior to, during and after a Postgraduate Certificate in Education course [PDF]

, 2004
Office for Standards in Education (OFSTED) inspections of secondary Postgraduate Certificate in Education (PGCE) physical education courses in England between 1996 and 1998 (OFSTED, 1999) were critical of student teachers' subject knowledge.
Calderhead J, Cathy Gower, Dodds P, Graber KC, Grossman PL, Grossman PL, Hardy C, Housner LD, McDiarmid GW, Reeves S, Rossi T, Ryan C, Schempp P, Shulman LS, Siedentop D, Siedentop D, Susan Capel, Wilson SM   +17 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Perceptual-Cognitive Tasks Affect Landing Performance of Soccer Players at Different Levels of Fatigue

Applied Bionics and Biomechanics, 2022
Background. There is a possible interaction between the underlying mechanisms of perceptual-cognitive tasks and motor control. For example, landing biomechanics changed during perceptual-cognitive tasks undertaken at different levels of fatigue of the ...
Yuanyuan Ren, Guodong Wang, Lei Zhang, Aming Lu, Cenyi Wang   +4 more
doaj   +1 more source