Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Supporting family care partners during physical therapy care. [PDF]
Tucker GG +3 more
europepmc +1 more source
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross +3 more
wiley +1 more source
Trait mindfulness and aggressive behavior in physical education undergraduates: a cross-sectional serial mediation analysis of anger rumination and self-control. [PDF]
Cui H, Liu W, Li L.
europepmc +1 more source
Selective methane (CH4) photooxidation emerges from architectural decoupling of activation and preservation. Programmable organic semiconductor frameworks spatially organize oxidative flux and intermediate residence, separating reaction zones from product domains to synchronize activation strength with stabilization and establish a selective oxidation ...
Minxian Zhang +5 more
wiley +1 more source
The impact of exercise intervention on physical self-esteem of Chinese college students: a systematic review and meta-analysis. [PDF]
Wang M, Li D, Song Y, Kong H, Wu F.
europepmc +1 more source
Optoelectronic Nanofluidic Neural Networks for Ionic Computing
An ion‐based optoelectronic nanofluidic memristor enables neuromorphic computing in aqueous environments. With tunable ionic memory and multimodal synaptic plasticity, it realizes densely connected ionic neural networks capable of image classification, motion prediction, logic computation, and real‐time in‐sensor computing, advancing fully connected ...
Yaxin Huang +10 more
wiley +1 more source
Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation
LipidXplorer is a novel microfluidic platform which enables rapid navigation of lipid particle design space for high‐resolution phase mapping, lipid nanoparticle optimization, membrane biophysics, and functional nanomaterial discovery. It combines programmable composition control, continuous nanoparticle formation, and automated well‐plate collection ...
Bradley Diggines +10 more
wiley +1 more source
Formal Educational Preparation and Continuing Professional Development Needs in Specialized Palliative Care Nursing: A Nationwide, Cross-Sectional Study. [PDF]
Košanski T +3 more
europepmc +1 more source
Angstrom‐Scale Confined Ion Sieve and Accelerator for Efficient Aqueous Zinc Batteries
An angstrom‐scale confined ion accelerator strategy is proposed for ultra‐stable aqueous Zn anodes. Selective and precise transport of hydrated Zn(H2O)62+, Zn2+ cations, H2O molecules, and SO42− anions is achieved by in‐plane atomic Ti vacancies and angstrom‐scale interlayer free spacing within the Ti0.87O2 interfacial layer, leading to homogeneous Zn ...
Xing Peng +16 more
wiley +1 more source

