Results 91 to 100 of about 97,017 (265)

Age-Dependent Differences of Paraspinal Muscle Endurance and Morphology in Chinese Community Population Without Chronic Low Back Pain

Global Spine Journal
Study Design: Cross-sectional study. Objectives: Our aim was to describe age-dependent changes of lumbar paraspinal muscle endurance and morphology in Chinese healthy population.
Gengyu Han MD, Wei Wang MD, Lihao Yue PhD, Zheyu Fan B.Eng, Zonglin Li BS, Jiaming Li MS, Zhuoran Sun MD, Weishi Li MD   +7 more
doaj   +1 more source

Effect of Tai Chi on muscle strength, physical endurance, postural balance and flexibility: a systematic review and meta-analysis. [PDF]

BMJ Open Sport Exerc Med, 2021
Wehner C, Blank C, Arvandi M, Wehner C, Schobersberger W.   +4 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Biochemical aspects of KB-28 compound on physically loaded study subjects

Current Issues in Pharmacy and Medical Sciences, 2019
In previous studies of actoprotective activity of 5-R-thio-tetrazolo[1,5]quinazoline derivatives in normal and complicated experimental conditions, sodium 2-(tetrazolo [1,5-c]quinazoline-5-ylthio)acetate (KB-28) was found to be the leader of the ...
Toziuk Olena, Krasna Olga, Kryvoviaz Olena, Rodinkova Victoria, Melnyk Andrii, Ivko Tanya, Voronkina Alona, Hutsol Viktoriia   +7 more
doaj   +1 more source

Effects of Ashwagandha ( <i>Withania somnifera</i>) standardized root extract on physical endurance and VO _2max in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study. [PDF]

F1000Res, 2023
Verma N, Gupta SK, Patil S, Tiwari S, Mishra AK.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Short term creatine loading improves strength endurance even without changing maximal strength, RPE, fatigue index, blood lactate, and mode state

Anais da Academia Brasileira de Ciências
Creatine is consumed by athletes to increase strength and gain muscle. The aim of this study was to evaluate the effects of creatine supplementation on maximal strength and strength endurance.
EDILSON TADEU F. FURTADO, JOÃO PAULO L. DE OLIVEIRA, ISABELA S.B. PEREIRA, ELAYNE P. VEIGA, SANDRO F. DA SILVA, WILSON CÉSAR DE ABREU   +5 more
doaj   +1 more source

Impact of Behavioral Assessment and Re-Test as Functional Trainings That Modify Survival, Anxiety and Functional Profile (Physical Endurance and Motor Learning) of Old Male and Female 3xTg-AD Mice and NTg Mice with Normal Aging. [PDF]

Biomedicines, 2022
Castillo-Mariqueo L, Giménez-Llort L.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source