Results 101 to 110 of about 5,681,930 (294)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
ENDURANCE OF RATS WITH DISBIOZ IN EMOTIONAL-PHYSICAL STRESS
Medical academic journal, 2019 Stress loads in sport lead to the development of functional disorders of various body systems, including the digestive system. The use of pharmacological preparations for correction of dysbiotic states is very often. The aim of this work was to study the physical endurance of rats with dysbiosis with decreased and increased intestinal circadian rhythm (
A F Safonova +2 more
openaire +2 more sources
, 2020 Increasing physical activity has convincingly shown to reduce the risk of atrial fibrillation (AF). However, decades of repetitive bouts of prolonged and vigorous endurance exercise have recently emerged as a risk factor for AF in middle-aged male ...
Mont L, Niebauer J, Sareban M, Guasch E
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
PHYSICAL FITNESS OF ATHLETES UNDER ENDURANCE TRAINING
, 2023 Introduction Athletes must have high sports skills and endurance to achieve good results in the field. Therefore, endurance training is very important among athletes.
Xiaofang Sun (402841)
core +1 more source
PHYSICAL EXERCISE FOR POWER AND ENDURANCE VOLLEYBALL SPORT
Jambura Journal of Sports Coaching, 2020 The research aims to provide a program of influence on the improvement of the dominant physical component in volleyball sports, the dominant physical component in question consisting of arm muscle strength, abdominal muscle strength, leg muscle strength, heart-lung endurance, and leg muscle explosion power.
openaire +2 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Effect of endurance training on serum Apelin levels, C-reactive protein and insulin resistance index in middle-aged sedentary men [PDF]
فصلنامه ابن سینا, 2017 Background: Apelin is a novel adipokine that is closely related with insulin resistance. The aim of this study was to assess the effects of endurance training on Apelin, C-reactive protein (CRP) and insulin resistance index in middle-aged sedentary men ...
R soori +3 more
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