Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier+8 more
wiley +1 more source
The impact of atmospheric pollutants on the physical health of college students--based on physical examination data of college students from a certain university in Xi'an, Shaanxi Province, China. [PDF]
He J, Liu K, He Z.
europepmc +1 more source
The microscopic examination of coke in relation to other physical and chemical properties
B N Nandi, D. S. Montgomery
openalex +1 more source
Universal Proteomic Signature After Exercise‐Induced Muscle Injury in Muscular Dystrophies
ABSTRACT Objective Several neuromuscular disorders (NMDs) are characterized by progressive muscle damage and are marked by the elevation of circulating muscle proteins from activity‐related injury. Despite a diverse array of genetic drivers, many NMDs share similar patterns of exercise intolerance and higher concentrations of muscle injury proteins ...
Mads G. Stemmerik+5 more
wiley +1 more source
Perceived self-efficacy in physical examination skills, clinical practice experiences, and utilization of findings in care plans among senior nursing students: a cross-sectional study. [PDF]
Şanlialp Zeyrek A, Fidan Ö.
europepmc +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan+6 more
wiley +1 more source
Construction of a risk screening and visualization system for pulmonary nodule in physical examination population based on feature self-recognition machine learning model. [PDF]
Tian F, Lin Y, Wang L, Fang F, Hou K.
europepmc +1 more source
Correspondence of MRI and nTMS With EDSS in Multiple Sclerosis: Longitudinal Follow‐Up Study
ABSTRACT Objectives Considering the characteristics of multiple sclerosis (MS) disease and its impact on motor disability, this study aims to assess the functional integrity of the corticospinal tract by examining motor evoked potentials (MEPs), Expanded Disability Status Scale (EDSS) scores, magnetic resonance imaging (MRI) lesion counts, and ...
Antonia Bralić+13 more
wiley +1 more source
Exploration of biomarkers for nursing physical examination early screening of multiple tumors. [PDF]
Li X, Li R.
europepmc +1 more source