Results 201 to 210 of about 2,296,541 (319)

Joint trajectories of objective physical function and cognition and risk of incident dementia: a population-based cohort study. [PDF]

Front Psychiatry
Wang S, Wang X, Zhou J, Zhou L.
europepmc   +1 more source

Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier, Ugo Sorrentino, Matias Wagner, Marta Zawadzka, Anna Lemska, Maria Mazurkiewicz‐Bełdzińska, Michael Zech   +6 more
wiley   +1 more source

The association between hyperkyphosis and physical function in geriatric outpatients with frailty. [PDF]

Arch Osteoporos
Koelé MC, van der Velde N, van Campen JPCM, van Haelst SAE, Willems HC.   +4 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Air Pollution and the Progression of Physical Function Limitations and Disability in Aging Adults. [PDF]

JAMA Netw Open
Gao J, Mendes de Leon CF, Szpiro AA, Weuve J, Langa KM, Hirth RA, Bakulski KM, Lee J, Zhang B, D'Souza J, Keller KP, Kaufman JD, Faul J, Adar SD.   +13 more
europepmc   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Corrigendum: Socioecological influencers of health-promoting lifestyles in Chinese: a preliminary survey using convenient samples

Frontiers in Public Health
Li Huang, Li Huang, Hansen Li, Haowei Liu, Haodong Tian, Haoyue Luo, Jinlong Wu, Yue Luo, Li Peng, Li Peng, Liya Guo, Liya Guo   +11 more
doaj   +1 more source

Baseline Functional Performance Predicts Better Long-Term Self-Reported Physical Function After Auto-HSCT. [PDF]

J Clin Med
Anderson LJ, Okamura L, Dhunjishah N, Gowrisankar R, Song J, Chauncey TR, Garcia JM.   +6 more
europepmc   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Association of physical function and sleep with oxidative stress in adults with chronic pain: A pragmatic clinical trial secondary analysis. [PDF]

J Int Med Res
Snow TJ, Shimada S, Ieronimakis N, Tintle N, Flynn DM, Wi D, Ransom JC, McQuinn HM, Doorenbos AZ.   +8 more
europepmc   +1 more source