Results 281 to 290 of about 602,686 (344)
LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5
Advanced Science, EarlyView.Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li +27 more
wiley +1 more source
Advanced Science, EarlyView.The complex centered on Ghd7 binds to numerous carbon and nitrogen metabolism genes on the genome through the corresponding motifs and transactivates the transcriptional expression of these carbon and nitrogen metabolism genes. With the assistance of OsNAC42 and other unknown Ghd7‐interacting proteins, this complex can regulate different metabolic ...
Guangming Lou +23 more
wiley +1 more source
A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication
Advanced Science, EarlyView.A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang +8 more
wiley +1 more source
Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label
Advanced Science, EarlyView.The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong +11 more
wiley +1 more source
Advanced Science, EarlyView.The main process of the eutectic molten salt method and the direct regeneration of Spent lithium (Li)‐ion batteries by the eutectic molten salt method have brought structural, performance, environmental, and economic benefits. Abstract The rapid growth of electric vehicles (EVs) has significantly increased the demand for lithium (Li)‐ion batteries ...
Junyi Wang +3 more
wiley +1 more source
Transparent and Transient Flexible Electronics
Advanced Science, EarlyView.Transparent electronics has gained tremendous attention in recent years because of the growing demand for see‐through devices in applications such as displays, windscreens, and wearables. This review discusses the recent developments related to transparent electronics as well as the challenges associated with the development of flexible and transient ...
Nitheesh M. Nair +2 more
wiley +1 more source
BMSC‐NFMC Model for Vascular Regulation and Interface Integration in Osteochondral Regeneration
Advanced Science, EarlyView.A novel strategy for integrated osteochondral tissue regeneration using BMSC‐NFMCs, this study has demonstrated the precise regulation of vascularization and effective interface integration using optimized nanofibrous materials and innovative construction methods.
Qian Zhou +8 more
wiley +1 more source
Advanced Science, EarlyView.Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo +11 more
wiley +1 more source