Results 21 to 30 of about 21,771,545 (251)

Study on Optimization of Structure of Porous Lateral Flow Storage Tank

Applied Sciences
Sediment buildup in storage tanks over extended operation periods may compromise their efficiency. To prevent pollutant deposition in storage tanks and enhance their hydraulic self-cleaning efficiency, this study addressed the unique structural ...
Qiwen Gao, Jiangang Feng, Hui Xu, Rui Zhang   +3 more
doaj   +1 more source

MATHEMATICAL MODEL OF RESOURCE DISTRIBUTION OF THE COMPUTING CLUSTER OF CLOUD DATA CENTERS

Современная наука и инновации, 2022
The subject of the study is the distribution and load balancing systems of computing clusters of cloud data centers (data centers) containing a variety of servers, data storage systems, I/O system interconnected by a communication network.
V. P. Mochalov, G. I. Linets, N. Y. Bratchenko, I. S. Palkanov   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Physical Experimental Study on the Wave Reflection and Run-Up of a New Ecological Hollow Cube

Journal of Marine Science and Engineering
Implementing quadrangular hollow blocks on breakwaters is a common method for wave mitigation and ocean disaster prevention. In order to improve the wave-damping performance of conventional quadrangular hollow blocks, a new quadrangular hollow block is ...
Haitao Zhao, Feiyue Ding, Junwei Ye, Huabin Jiang, Wei Chen, Weifang Gu, Gengfeng Yu, Qiang Li   +7 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

FBG and BOTDA Based Monitoring of Mine Pressure Under Remaining Coal Pillars Using Physical Modeling

Sensors
Strong mine pressure often emerges when the working face of the lower coal seam in a closely spaced coal seam system passes through the remaining coal pillar in the overlying goaf.
Dingding Zhang, Zhi Li, Yanyan Duan, Long Yang, Hongrui Liu   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source