Results 51 to 60 of about 21,771,545 (251)

Synchronisation of the ensemble of nonidentical FitzHugh–Nagumo oscillators with memristive couplings [PDF]

Известия высших учебных заведений: Прикладная нелинейная динамика
The aim of the study is to investigate the features of synchronization in ensembles of nonidentical neuron-like FitzHugh–Nagumo oscillators interacting via memristor-based coupling. Methods.
Navrotskaya, Elena Vladimirovna, Kurbako, Aleksandr Vasilievich, Ponomarenko, Vladimir Ivanovich, Prokhorov, Mihail Dmitrievich   +3 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Numerical and Physical-Model Investigation of Landslide-Generated Surge Waves from a Localized Unstable Zone in the Yangqu Canyon Reservoir: Wave Generation and Propagation

Applied Sciences
Surge waves generated by rapid landslide entry into canyon reservoirs can threaten near-dam hydraulic structures. This study examines a representative post-failure hydrodynamic scenario for the localized unstable Zone B of the No.
Jianjun Xu, Shuwu Li, Fenghua Zhang, Pengfeng Li, Zhongjia Yang, Fei Ye   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

PENGGUNAAN FISIKAL MODEL DALAM PERANCANGAN ARSITEKTUR

, 2013
One important factor in architectural design process that are used is physical model. Information and design solutions for the architectural design process can be obtained using physical model.
model, architecture design, physical, Prawata, Albertus   +1 more
core  

Gust response: a validation experiment and preliminary numerical simulations [PDF]

, 2011
In this paper the experimental setup and first results for a gust generator experiment will be presented. The experiment was carried out in the transonic wind-tunnel facility in Goettingen (DNW-TWG).
Hennings, Holger, Neumann, Jens, Mai, Holger   +2 more
core  

Identification of relaxation parameter of a physical model of vein from fluid transient experiment

EPJ Web of Conferences, 2014
This paper presents a new fluid transient inflation experiment applied on a physical model of vein (short latex tube, 5mm diameter). Aim of experiments is assessment of wall viscous behaviour from attenuated pulsation of the tested sample.
Hromádka David, Chlup Hynek, Žitný Rudolf   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Physical Model Experiment on Offshore Breakwater Project in Dongao Bay

Renmin Zhujiang, 2020
Dongao Bay Breakwater Project is an important infrastructure for Zhuhaiisland development, which is of great significance to the development of inhabitedislands in Zhuhai.
CHEN Kai, HE Yong, WANG Shijun
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source